Rhabdomyosarcama of the middle ear and mastoid

Pahor, A. L.

doi:10.1017/s0022215100082487

Cited by 11 publications

(3 citation statements)

References 48 publications

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“…The age of rats reported with rhabdomyosarcomas ranges from 90 to 123 weeks with a median age of 103 weeks (Conner, 1994). This is in contrast to humans, where rhabdomyosarcomas are usually most frequent in children, but uncommon in adults (Jaffe et al., 1971; Pahor, 1976). There is no sex dominance or predilection for either the right or left ear side in human (Jaffe et al., 1971).…”

Section: Discussionmentioning

confidence: 66%

“…In animals, rhabdomyosarcomas are most often seen in the heart and lower extremities, but also known to occur in other locations, such as the ear, kidney, lung, urinary bladder and uterus (Cooper and Valentine, 2002). In human, rhabdomyosarcoma of the ear is a malignant tumour that occurs almost exclusively in children (Jaffe et al., 1971; Pahor, 1976). In animals, ear (auricular) rhabdomyoma has been reported in cats (Roth, 1990).…”

Section: Introductionmentioning

confidence: 99%

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Auricular Rhabdomyosarcoma in a Rat

Radi

2006

Journal of Veterinary Medicine Series A

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An ear (auricular) neoplasm from a 1-year-old male rat was removed surgically and examined histologically. Macroscopically, the neoplasm was firm, white and measured (0.5 x 0.5 cm). Microscopically, the neoplasm was expansile, non-encapsulated, and composed of large, pleomorphic, polygonal to spindle-shaped cells containing multiple nuclei. Using immunohistochemical and chemical stains, the neoplastic cells were positive for vimentin, myoglobin, phosphotungstic acid haematoxylin and desmin, but had no immunoreactivity for cytokeratin or alpha-smooth muscle actin. On the basis of histopathological, immunohistochemical and histochemical stains, a diagnosis of auricular rhabdomyosarcoma was made. Although reported infrequently in human, this is, to the author's knowledge, the first report that describes the detailed gross, histopathological, histochemical and immunohistochemical findings of auricular rhabdomyosarcoma in a rat.

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Section: Discussionmentioning

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Auricular Rhabdomyosarcoma in a Rat

Radi

2006

Journal of Veterinary Medicine Series A

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“…Middle ear and mastoid involvement accounts for about 8 per cent of head and neck rhabdomyosarcomas (Sutow et al, 1982). Up to 1976 there had been only 72 cases reported in the English literature (Pahor, 1976). Since then a few reports have appeared (El-Shannawy and Khafagy, 1979;De, 1979;El-Shannawy era/., 1980;Proops and Mann, 1984).…”

Section: Incidencementioning

confidence: 99%