Rheological Experimentation to Investigate History Dependent Viscoelastic Properties of ex-vivo Ovine Brain Tissue

Tissue‐Scale Biomechanical Testing of Brain Tissue for the Calibration of Nonlinear Material Models

“…Regarding the diameter of cylindrical or ring‐shaped samples, either intermediate (5 mm ‐ 9 mm) (Calhoun et al., 2019; Distler et al., 2020; Franceschini et al., 2006; Greiner et al., 2021; Haslach et al., 2014; Hrapko et al., 2006; Hrapko et al., 2008a; Li et al., 2015; Li et al., 2021; Li et al., 2019; Li et al., 2020; Mihai et al., 2015; Mijailovic et al., 2021; Pogoda et al., 2014; Reiter et al., 2021; Zhao et al., 2016), relatively large (10 mm ‐ 19.05 mm) (Arbogast & Margulies, 1997; Arbogast & Margulies, 1998; Brands et al., 2000; Brands et al., 1999; Calhoun et al., 2019; Darvish & Crandall, 2001; Donnelly & Medige, 1997; Eskandari et al., 2021a; Eskandari et al., 2021b; Feng et al., 2013a; Forte et al., 2017; Franceschini et al., 2006; Galford & McElhaney, 1970; Hrapko et al., 2006; Hrapko et al., 2008a; Karimi & Navidbakhsh, 2014; Laksari et al., 2012; Li et al., 2016; Lilley et al., 2020; McElhaney et al., 1973; Nicolle et al., 2004; Pervin & Chen, 2009; Pervin & Chen, 2011; Peters et al., 1997; Rashid et al., 2012e; Rashid et al., 2012a; Rashid et al., 2012f; Rashid et al., 2012c; Rashid et al., 2012d; Rashid et al., 2012b; Rashid et al., 2014; Shafieian et al., 2012; Shuck & Advani, 1972; Tamura et al., 2008; Thibault & Margulies, 1996; Thibault & Margulies, 1998; Zhang et al., 2011a), very large (20 mm ‐ 30 mm) (Balbi et al., …”

“…To characterize the mechanical properties of individual regions of the brain using multi‐modal mechanical testing, brain tissue has to be cut into suitable samples. Most researchers have used samples with a circular (Arbogast et al., 1995; Arbogast & Margulies, 1997; Arbogast & Margulies, 1998; Balbi et al., 2019; Bilston et al., 2001; Bilston et al., 1997; Brands et al., 2000; Brands et al., 1999; Calhoun et al., 2019; Canovic et al., 2016; Chatelin et al., 2012; Cheng & Bilston, 2007; Clemmer et al., 2016; Darvish & Crandall, 2001; Distler et al., 2020; Donnelly & Medige, 1997; Eskandari et al., 2021a; Eskandari et al., 2021b; Estes & MacElhaney, 1970; Feng et al., 2013a; Forte et al., 2017; Franceschini et al., 2006; Galford & McElhaney, 1970; Garo et al., 2007; Greiner et al., 2021; Haslach et al., 2014; Hosseini‐Farid et al., 2017; Hosseini‐Farid, 2019; Hosseini‐Farid et al., 2019; Hrapko et al., 2006; Hrapko et al., 2008a; Karimi & Navidbakhsh, 2014; Laksari et al., 2012; Li et al., 2016; Li et al., 2015; Lilley et al., 2020; Li et al., 2021; Li et al., 2019; Li et al., 2020; McElhaney et al., 1973; Metz et al., 1970; Mihai et al., 2015; Mijailovic et al., 2021; Miller & Chinzei, 2002; Miller & Chinzei, 1997; Navarro‐Lozoya et al., 2019; Nicolle et al., 2004; Peters et al., 1997; Pogoda et al., 2014; Prabhu et al., 2009; Prabhu et al., 2011; Prabhu et al., 2019; Rashid et al., 20...…”

“…Due to similarities with the human brain (Lewis et al., 1996), several researchers also studied ovine brain under compression (Felfelian et al., 2019; Hosseini‐Farid et al., 2017; Zhang et al., 2018), tension (Labus & Puttlitz, 2016a; Labus & Puttlitz, 2016b), shear (Lilley et al., 2020), and indentation (Feng et al., 2013b; Kobielarz et al., 2011; Szotek et al., 2007). Further studies on mammalian brains determined the mechanical properties of caprine (Pervin & Chen, 2011), dog (Samadi‐Dooki et al., 2018; Zhang et al., 2016a; Zhang et al., 2016c), rat (Elkin et al., 2010; Elkin et al., 2011; Elkin & Morrison III, 2013; Finan et al., 2012a; Finan et al., 2012b; Gefen et al., 2003; Haslach et al., 2014; Karimi & Navidbakhsh, 2014; Lee et al., 2011; Lee et al., 2014; MacManus et al., 2017b; MacManus et al., 2020; Shafieian et al., 2009), and murine brain tissue (Canovic et al., 2016; Dodgson, 1962; MacManus et al., 2015; MacManus et al., 2016; MacManus et al., 2017a; MacManus et al., 2017b; MacManus et al., 2017c; MacManus et al., 2018; MacManus et al., 2020; Mihai et al., 2015; Mijailovic et al., 2021; Pogoda et al., 2014).…”

“…Donnelly & Medige, 1997;Eskandari et al, 2021a;Eskandari et al, 2021b;Feng et al, 2013a;Forte et al, 2017;Franceschini et al, 2006;Galford & McElhaney, 1970;Hrapko et al, 2006;Hrapko et al, 2008a;Karimi & Navidbakhsh, 2014;Laksari et al, 2012;Li et al, 2016;Lilley et al, 2020;McElhaney et al, 1973;Nicolle et al, 2004;Pervin & Chen, 2009;Pervin & Chen, 2011;Peters et al, 1997;Rashid et al, 2012e;Rashid et al, 2012a;Rashid et al, 2012f;Rashid et al, 2012c;Rashid et al, 2012d;Rashid et al, 2012b;Rashid et al, 2014;Shafieian et al, 2012;Shuck & Advani, 1972;Tamura et al, 2008;Thibault & Margulies, 1996;Thibault & Margulies, 1998;Zhang et al, 2011a), very large (20 mm -30 mm)(Balbi et al, 2019;Bilston et al, 2001;Bilston et al, 1997;Canovic et al, 2016;Chatelin et al, 2012;Cheng & Bilston, 2007;Clemmer et al, 2016;Darvish & Crandall, 2001;…”