Rheological Properties and Its Effect on the Lubrication Mechanism of PVP K30 and PVP 40-50 G as Artificial Synovial Fluids

Abstract

The effect of polyvinylpyrrolidone (PVP) on the rheological properties of joint prostheses is still unclear, despite its good lubricity and biocompatibility. In the present work, PVP K30 and PVP 40-50 G solutions at different concentrations were analyzed for rheological and lubrication properties. The rheological properties of the samples were measured at a shear rate range of 0–1800 s−1 (advanced air bearing rheometer Bohlin Gemini 2 and Plate MCR 72/92 rheometer for PVP30 and PVP 40-50 G, respectively). It was found that both the viscosity and shear stress of the samples reduced with a shear rate increase. PVP 40-50 G/sterile water showed higher viscosity as compared to the PVP K30/sterile water sample at a lower shear rate. However, at a higher shear rate, the PVP K30 sample produced better results. Further numerical study results showed the pressure and molecular viscosity distributions. The inclusion of PVP improved the load caring capacity and hence, it is a promising lubrication additive for artificial joints.

Bioactive Materials Based on Hydroxypropyl Methylcellulose and Silver Nanoparticles: Structural-Morphological Characterization and Antimicrobial Testing

“…Hence, the addition of PVP in the system will lead to an intensification of the physical and chemical interactions, thereby having impact on the rheological characteristics of the systems. As the PVP ratio in the blend increased from 5 to 30 wt.%, the blends exhibited an enhancement of the rheological properties, revealing the role of PVP as a polymeric stabilizer, due to the strong polarity and hydrophilic properties [ 57 , 58 ]. Consequently, the different and complex rheological behavior can be explained by taking into account the synergism between the structural characteristics of both HPMC and PVP, which in turn depends on the packing efficiency and specific interactions.…”

Development and Characterization of Nanofiber Strip Containing Sertraline for Buccal Application

“…The findings were consistent with our research. According to Figures 1 and 2, shearing stress and viscosity change in relation to shearing rate, with shearing stress increasing in Figure 1 and viscosity decreasing in Figure 2, respectively (Kotia et al, 2021) The PVP ratio in the polymer solutions without sertraline affected the conductivity values. The resultant formulation, which contained 30 mg of sertraline and 5% PVP, had the highest conductivity score.…”