2023
DOI: 10.1037/bne0000525
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Rhesus monkeys with damage to amygdala or orbitofrontal cortex perform well on novelty-based memory tasks.

Abstract: The amygdala and orbitofrontal cortex (OFC) are interconnected regions that serve as key nodes in brain circuits supporting social and affective behaviors. An important question that has come into focus is whether these regions also play a fundamental role in responding to novelty. One possibility is that these regions are important for discriminating novel from familiar stimuli. An alternative possibility is that these regions contribute to affective responses to stimuli in novelty-based tasks. For example, t… Show more

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