Rheumatic heart disease: The cost of late diagnosis

Gentles, Thomas L.; Wilson, Nigel

doi:10.1016/j.ijcard.2021.10.158

Cited by 6 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…regurgitation or stenosis) of the mitral and aortic valves are evaluated, as detailed in the World Heart Federation (WHF) criteria for diagnosis ( 12 ). This screening and potentially early diagnosis could offer a timely opportunity to provide secondary prophylaxis to prevent progression or, if needed, interventional treatment for a patient at a less advanced stage of disease ( 2 , 13 , 14 ). Recently, Beaton et al conducted a randomized controlled trial in Uganda and found that the use of secondary prophylaxis (i.e.…”

Section: Why Use Echocardiographic Screening For Rheumatic Heart Dise...mentioning

confidence: 99%

The role of echocardiographic screening in reducing the burden of rheumatic heart disease in Latin America

Urina-Jassir,

Jaimes-Reyes,

Urina-Jassir

et al. 2023

Revista Panamericana De Salud Pública

View full text Add to dashboard Cite

The objectives of this article are to reflect on the rationale behind the use of echocardiographic screening for rheumatic heart disease and to provide key recommendations about steps needed to implement and improve echocardiographic screening programs in Latin America. Rheumatic heart disease remains a public health problem affecting mainly low-income and lower-middle-income countries and populations. Latin America is an area with economic inequalities, and the epidemiology of rheumatic heart disease remains largely unknown. Echocardiographic screening is useful for updating the epidemiology and providing early diagnosis of the disease. We discuss different approaches used in successful echocardiographic screening programs worldwide and in Latin America. We then identify the key elements needed to establish successful echocardiographic screening programs in Latin America, including increased awareness and involvement from multiple sectors (e.g. the community, health care professionals, scientific organizations and public health entities), identification of areas in need, development of a plan and structure that include different screening approaches, and how to ensure appropriate follow up for those who screen positive.

show abstract

Section: Why Use Echocardiographic Screening For Rheumatic Heart Dise...mentioning

confidence: 99%

The role of echocardiographic screening in reducing the burden of rheumatic heart disease in Latin America

Urina-Jassir,

Jaimes-Reyes,

Urina-Jassir

et al. 2023

Revista Panamericana De Salud Pública

View full text Add to dashboard Cite

show abstract

“…Over several decades, the disease progression leads to valvular stenosis or regurgitation, resulting in structural cardiac abnormalities [ 4 ]. It is a major cause of preventable premature deaths and is a significant burden to the healthcare system [ 5 ], and the majority of ARF cases occur in low-middle-income countries.…”

Section: Introductionmentioning

confidence: 99%

Temporal Trends of Age-Adjusted Mortality Rates for Rheumatic Heart Disease in Brazil From 2000 to 2021

McBenedict,

Mansoor,

Chaudhary

et al. 2024

Cureus

View full text Add to dashboard Cite

Background Rheumatic heart disease (RHD) is a chronic cardiovascular condition stemming from an infectious origin, posing a substantial health burden, particularly in economically disadvantaged regions. It starts with acute rheumatic fever (ARF), a complication following group A Streptococcus infection, leading to heart valve damage and, over time, structural heart abnormalities. RHD contributes to premature deaths, especially in low-middle-income countries. Although the incidence and prevalence have generally reduced globally due to antibiotics and improved healthcare, it remains a significant public health concern in Brazil, echoing its prevalence in many developing nations around the world. RHD stands as a poignant testament to the intersection of socio-economic disparities and healthcare challenges within Brazil's diverse population. In Brazil, despite advancements in healthcare, RHD continues to impact communities, highlighting the urgent need for enhanced prevention strategies, access to quality healthcare services, and heightened awareness to combat this preventable, yet persistent, cardiac condition. Understanding the epidemiological landscape and socio-cultural factors influencing RHD in Brazil is crucial for developing targeted interventions aimed at mitigating its burden on individuals, families, and the healthcare system at large. Thus, our study focuses on analyzing age-related mortality rates linked to ARF and chronic RHD (ARHD) in Brazil from 2000 to 2021, particularly examining gender disparities. Materials and methods This retrospective cohort study employed a descriptive time-series approach, utilizing comprehensive nationwide data from Brazil spanning from 2000 to 2021 to assess trends in diverse age groups, among both sexes, enabling a detailed analysis of temporal patterns. Mortality data, extracted and categorized meticulously, were subjected to Joinpoint statistical analyses enabling comparative assessments, with average annual percent change (AAPC) and annual percent change (APC) serving as key metrics to quantify and interpret trends over the analyzed period. Results The acute RHD (ARHD)-related mortality declined over the analyzed years supported by AAPC, with higher mortality reduction in females. The age-adjusted mortality rate for "males and females" decreased from 78 to 67 deaths/100,000 from 2000 to 2021. Female mortality dropped from 85 to 69/100,000, and male mortality decreased from 73 to 63/100,000 over the same period. For ARHD, male age groups (20-29, 60-69, 70-79, 80+) showed declining mortality, while the 30-59 age group exhibited an upward. Females AAMR for chronic RHD (CRHD) decreased across all age groups, with significant reductions in the 80 years and above age group from 2000-2002 (APC: -11.94*) and steadily from 2002 onwards (APC: -1.33). Conclusions Our study revealed an overall decline in mortality rates for both acute and CRHD across both sexes. Females consistently exhibited higher ...

show abstract

Association Between the Expression of T Helper Type 17 Cell-Related Cytokines and Valve Damage in Rheumatic Heart Disease

Zhang,

Xiao,

Yang

2024

Mol Biotechnol

View full text Add to dashboard Cite

Rheumatic heart disease: The cost of late diagnosis

Cited by 6 publications

References 10 publications

The role of echocardiographic screening in reducing the burden of rheumatic heart disease in Latin America

The role of echocardiographic screening in reducing the burden of rheumatic heart disease in Latin America

Temporal Trends of Age-Adjusted Mortality Rates for Rheumatic Heart Disease in Brazil From 2000 to 2021

Association Between the Expression of T Helper Type 17 Cell-Related Cytokines and Valve Damage in Rheumatic Heart Disease

Contact Info

Product

Resources

About