Rheumatic silent carditis: Echocardiographic diagnosis and prognosis of long‐term follow up

Pekpak, Esra; Atalay, Semra; Karadeniz, Cem; Demir, Fikri; Tutar, Ercan; Uçar, Tayfun

doi:10.1111/ped.12163

Cited by 14 publications

(8 citation statements)

References 23 publications

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“…In one study, the prevalence of subclinical carditis following the first episode of ARF was 18% and half of the patients had persistence or deterioration of disease 2–23 months later 178 . Studies by Araujo and colleagues 179 and Pekpak and colleagues 180 reported that the proportion of patients with subclinical ARF who had persistence of carditis at least 1 year later was 72% and 55%, respectively.…”

Section: Diagnosis Screening and Preventionmentioning

confidence: 99%

Acute rheumatic fever and rheumatic heart disease

Carapetis

Beaton

Cunningham

et al. 2016

Nat Rev Dis Primers

483

486

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Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused by infection with group A Streptococcus. The long-term damage to cardiac valves caused by ARF, which can result from a single severe episode or from multiple recurrent episodes of the illness, is known as rheumatic heart disease (RHD) and is a notable cause of morbidity and mortality in resource-poor settings around the world. Although our understanding of disease pathogenesis has advanced in recent years, this has not led to dramatic improvements in diagnostic approaches, which are still reliant on clinical features using the Jones Criteria, or treatment practices. Indeed, penicillin has been the mainstay of treatment for decades and there is no other treatment that has been proven to alter the likelihood or the severity of RHD after an episode of ARF. Recent advances — including the use of echocardiographic diagnosis in those with ARF and in screening for early detection of RHD, progress in developing group A streptococcal vaccines and an increased focus on the lived experience of those with RHD and the need to improve quality of life — give cause for optimism that progress will be made in coming years against this neglected disease that affects populations around the world, but is a particular issue for those living in poverty.

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Section: Diagnosis Screening and Preventionmentioning

confidence: 99%

Acute rheumatic fever and rheumatic heart disease

Carapetis

Beaton

Cunningham

et al. 2016

Nat Rev Dis Primers

483

486

View full text Add to dashboard Cite

show abstract

“…Unless in severe pulmonal hypertension due to various causes, Marfan syndrome and aortic aneurism, surgery should be performed electively. However, intensive care is needed during postpartum period [33].…”

Section: Discussionmentioning

confidence: 99%

A Case: Optimal Treatment of Pregnancy with Rheumatic Heart Disease

oktaliani¹,

D²

2020

J Gynecol Res Rev Rep

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The number of women who have a pre-existing cardiovascular disease (CVD) or develop cardiac problems during pregnancy is increasing, and it is the leading cause of non-obstetric mortality during pregnancy. Heart disease complicates approximately 1–3% of pregnancies and is responsible for 10 to 15% of maternal mortality. The rheumatic heart disease remains the number one worldwide cause of maternal cardiac complications in pregnant. It is important that obstetric, anesthesiologists, cardiologist, remain aware of the disease, its complications and management of valvular lesions throughout the birthing process.

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“…34 Moreover, we previously reported the progression of valvular regurgitation in 6 children (30%) among 20 children who were diagnosed with subclinical rheumatic heart disease, after a follow-up of 43.4 ± 25 months. 41 Therefore, we suggest long-term penicillin prophylaxis in children with subclinical rheumatic heart disease. It is known that secondary prophylaxis improves the prognosis of this disease and prevents recurrence.…”

Section: Discussionmentioning

confidence: 99%

Echocardiographic screening for rheumatic heart disease in Turkish schoolchildren

et al. 2019

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Background:The aim of this study is to investigate the prevalence of subclinical rheumatic heart disease in schoolchildren aged 5–18 by using portable echocardiography in Ankara, Turkey.Methods:The portable echocardiography screening was performed by a paediatric cardiologist for all of the cases. The mean age of 2550 healthy students was 11.09 ± 2.91 years (1339 females, 1211 males) in three private and three public schools. Echocardiographic studies were assessed according to 2012 World Heart Federation criteria for rheumatic heart disease.Results:After reviewing the echocardiographic images, 73 students were reevaluated by an advanced echocardiography device in the university hospital. Evidence of definite subclinical rheumatic heart disease was found in 39 students (15/1000) and borderline rheumatic heart disease in 20 students (8/1000). No children had any clinical symptoms. The mean age of children diagnosed with rheumatic heart disease and borderline rheumatic heart disease is 12.4 and 11.4 years, respectively. The risk of rheumatic heart disease was found to be increased sevenfold in girls between 14 and 18 years. We surprisingly observed that the prevalence of definite rheumatic heart disease in private schools located in high-income areas of Ankara was higher than that in public schools.Conclusions:This is the first and largest single-centred echocardiographic screening study for subclinical rheumatic heart disease in Turkish schoolchildren. The frequency of rheumatic heart disease has been found to be 15/1000. This finding is similar to those of recent echocardiographic screening studies performed in middle and high-risk populations. We conclude that to decrease the burden of rheumatic heart disease, echocardiographic screening studies are necessary, and long-term follow-up of children with echocardiographically diagnosed subclinical rheumatic heart disease is needed.

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Rheumatic silent carditis: Echocardiographic diagnosis and prognosis of long‐term follow up

Abstract: It is suggested that Doppler echocardiography be performed in all patients with suspected acute rheumatic fever for early detection of SC. Echocardiography should be used as a diagnostic criterion in order not to miss a diagnosis of SC.

Cited by 14 publications

References 23 publications

Acute rheumatic fever and rheumatic heart disease

Acute rheumatic fever and rheumatic heart disease

A Case: Optimal Treatment of Pregnancy with Rheumatic Heart Disease

Echocardiographic screening for rheumatic heart disease in Turkish schoolchildren

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