Rheumatoid arthritis: a psychiatric assessment.

Baker, Gertrude; Brewerton, D. A.

doi:10.1136/bmj.282.6281.2014

Cited by 30 publications

(6 citation statements)

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“…Similarly, adolescents with asthma tend to report higher levels of psychological stress than adolescents without the disease (29). A few studies have also shown increased susceptibility among individuals with high stress levels to other inflammatory diseases such as rheumatoid arthritis (30) and inflammatory bowel disease (31).…”

Section: Discussionmentioning

confidence: 97%

The Relationship between Perceived Stress and Morbidity among Adult Inner-City Asthmatics

et al. 2010

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Background. Psychological stress has been linked in some studies to asthma prevalence and outcomes in children. The authors sought to evaluate the relationship between perceived stress and morbidity among inner-city adults with asthma. Methods. The authors interviewed a prospective cohort of 326 moderate-to-severe asthmatics receiving care at two large, urban, hospital-based general medicine clinics in New York City and New Jersey. Psychological stress was assessed at baseline using the Perceived Stress Scale (PSS), a validated 4-item instrument. Outcomes included the Asthma Control Questionnaire (ACQ), the Asthma Quality of Life Questionnaire (AQLQ), and the Medication Adherence Reporting Scale (MARS) measured at baseline, 1, 3, and 12 months of enrollment. Results. Higher perceived stress was significantly correlated with worse asthma control (ACQ scores; r = .30 to .37, p < .0001), poor quality of life (AQLQ scores; r = -.49 to - .35, p < .0001), and decreased medication adherence (MARS scores; r = -.25 to -.15, p < .028) at baseline and across the follow-up interviews. In multivariate analyses, increased stress remained a significant predictor of worse ACQ (p < .0001), AQLQ scores (p < .0001), and MARS (p < .0001) after adjusting for age, sex, income, number of years with asthma, and comorbidities. Conclusions. Among inner-city asthmatics, higher perceived stress is strongly associated with increased asthma morbidity across a 1-year follow-up. Further research is needed to identify mechanisms mediating the association between stress and asthma morbidity in adults.

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Section: Discussionmentioning

confidence: 97%

The Relationship between Perceived Stress and Morbidity among Adult Inner-City Asthmatics

et al. 2010

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“…There is extensive evidence on stress‐induced alteration, both in immune‐mediated diseases, and in the immune function [7]. A few studies have shown increased susceptibility under stressful circumstances to acute and chronic inflammatory diseases, such as common cold [8], rheumatoid arthritis [9] and inflammatory bowel disease [10]. A positive association between stressful life events and the onset of asthma has been reported in some retrospective studies [11,12].…”

Section: Introductionmentioning

confidence: 99%

Stressful life events promote the manifestation of asthma and atopic diseases

Kilpeläinen¹,

Koskenvuo²,

Helenius

et al. 2002

Clin Experimental Allergy

129

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“…It has also been hypothesized that excessive emotional stress levels and subsequent stress hormone liberation may contribute to RA disease onset due to the potential damage inflicted on the immune system by catecholamines and cortisol (Kumar et al 1981, Rogers et al 1980. RA onset is reported to be associated with recent termination of marriage, recent family death, and loss of employment (King & Cobb 1958, Baker & Brewerton 1981. Schochet (1969) found that the stress factor most often associated with RA onset was 'a threatened or actual loss of a loved one which aroused feelings of rage which the person could not cope with or express'.…”

Section: A Disabling Diseasementioning

confidence: 97%

Stress factors, emotional stress and rheumatoid arthritis disease activity

Crosby

1988

Journal of Advanced Nursing

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The purpose of this study was to determine the relationship between stress factors, emotional stress and rheumatoid arthritis (RA) disease activity. Subjects (n = 101) confirmed to have RA completed the Daily Hassles Scale (DHS) to identify daily stress factors and the State/Trait Anxiety Inventory (STAI) as well as a visual analogue (VA) to measure emotional stress levels. The investigator evaluated RA disease activity (RADA) and erythrocyte sedimentation rate (ESR). Pearson product-moment correlation was used for statistical evaluation. A statistically significant, positive correlation was found between RADA and both measures of emotional stress; STAI r2 = 0.16, VA r2 = 0.25, P less than 0.01. Utilizing a psychophysiological feedback loop model, it was hypothesized that emotional stress levels and RA disease activity each served as a driving force and a consequence, i.e. as emotional stress levels increased, RA symptoms intensified and, likewise, as RA symptoms intensified, emotional stress levels increased. Nursing interventions were identified which possibly would reduce emotional stress levels, and thus, perhaps, decrease the incidence and/or severity of RA disease activity.

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Rheumatoid arthritis: a psychiatric assessment.

Abstract: Ketotifen overdose: surveillance of the toxicity of a new drug An error occurred in the table of this paper by Drs D B Jefferys and G N Volans (30 May, p 1775). The plasma concentrations of ketotifen should have been expressed in ,ug/l, not mg/I.

Cited by 30 publications

References 1 publication

The Relationship between Perceived Stress and Morbidity among Adult Inner-City Asthmatics

The Relationship between Perceived Stress and Morbidity among Adult Inner-City Asthmatics

Stressful life events promote the manifestation of asthma and atopic diseases

Stress factors, emotional stress and rheumatoid arthritis disease activity

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