Rheumatoid arthritis: glucocorticoids are associated with nearly double infection risk post-surgery

Mahase, Elisabeth

doi:10.1136/bmj.l2271

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…This is more vital if the patient is undertaking a revision operation, where the infection rates in patients with rheumatoid arthritis are greater (Bongartz et al 2008, Khan et al 2011). A recent review by Mahase (2019) found that use of glucocorticoids in patients with rheumatoid arthritis is associated with nearly double the infection risk postoperative.…”

Section: Postoperative Managementmentioning

confidence: 99%

Perioperative management of patients with rheumatoid arthritis undergoing orthopaedic surgery

Agarwal

Kamaraj

McDonnell

et al. 2019

Journal of Perioperative Practice

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Rheumatoid arthritis is an autoimmune disease which is characterised by systemic inflammation. In the recent decades, the advent of disease modifying anti-rheumatic drugs have reduced the need for orthopaedic procedures. However, there are numerous patients in which pharmacological treatment fails and these patients require surgical intervention. Complications can arise due to the underlying pathology and multitude of medications these patients can be on, specifically increased infection rates due to use of immunosuppressive agents. An understanding into the disease itself, as well as perioperative management, may improve overall patient outcomes and prevent future complications.

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Section: Postoperative Managementmentioning

confidence: 99%

Perioperative management of patients with rheumatoid arthritis undergoing orthopaedic surgery

Agarwal

Kamaraj

McDonnell

et al. 2019

Journal of Perioperative Practice

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show abstract

“…Given the risk of fractures, the researchers suggested that the addition of statins and TNF-α inhibitors, and the limited use of opioid, GCs and psychotropic drugs may reduce the risk of vertebral fractures in RA patients with cardiovascular disease and other joint fractures of RA patients ( Ozen et al, 2019 ). Furthermore, although most rheumatologists prefer bDMARDs and GCs to control the inflammatory response of RA, they increase the risk of double infection after joint replacement or during routine treatment compared to csDMARDs and other RA drugs ( George et al, 2019 ; Mahase, 2019 ). In conclusion, we suggest that rheumatologists should provide patients with a rational western drug treatment regimen for RA according to the latest official guidelines.…”

Section: Introductionmentioning

confidence: 99%

Practical Implementation of Artificial Intelligence-Based Deep Learning and Cloud Computing on the Application of Traditional Medicine and Western Medicine in the Diagnosis and Treatment of Rheumatoid Arthritis

Wang

Hou

et al. 2021

Front. Pharmacol.

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Rheumatoid arthritis (RA), an autoimmune disease of unknown etiology, is a serious threat to the health of middle-aged and elderly people. Although western medicine, traditional medicine such as traditional Chinese medicine, Tibetan medicine and other ethnic medicine have shown certain advantages in the diagnosis and treatment of RA, there are still some practical shortcomings, such as delayed diagnosis, improper treatment scheme and unclear drug mechanism. At present, the applications of artificial intelligence (AI)-based deep learning and cloud computing has aroused wide attention in the medical and health field, especially in screening potential active ingredients, targets and action pathways of single drugs or prescriptions in traditional medicine and optimizing disease diagnosis and treatment models. Integrated information and analysis of RA patients based on AI and medical big data will unquestionably benefit more RA patients worldwide. In this review, we mainly elaborated the application status and prospect of AI-assisted deep learning and cloud computation-oriented western medicine and traditional medicine on the diagnosis and treatment of RA in different stages. It can be predicted that with the help of AI, more pharmacological mechanisms of effective ethnic drugs against RA will be elucidated and more accurate solutions will be provided for the treatment and diagnosis of RA in the future.

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Rheumatoid arthritis: glucocorticoids are associated with nearly double infection risk post-surgery

Cited by 2 publications

References 2 publications

Perioperative management of patients with rheumatoid arthritis undergoing orthopaedic surgery

Perioperative management of patients with rheumatoid arthritis undergoing orthopaedic surgery

Practical Implementation of Artificial Intelligence-Based Deep Learning and Cloud Computing on the Application of Traditional Medicine and Western Medicine in the Diagnosis and Treatment of Rheumatoid Arthritis

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