Rheumatology training and research in Iran

Khabbazi, Alireza; Soroosh, Mohsen

doi:10.1007/s00296-019-04325-5

Cited by 4 publications

(4 citation statements)

References 75 publications

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“…Powel et al reported more prevalence of PR and concluded that for each of the two patients of new RA onset at their centre, one patient of PR was diagnosed 7 . In our report of a cohort of inflammatory arthritis, the prevalence of PR was 2.8% of all inflammatory arthritis 8 . In the Azar cohort, we reported the prevalence of PR at 4 in 1000 of general population 9 .…”

Section: Introductionmentioning

confidence: 62%

“…7 In our report of a cohort of inflammatory arthritis, the prevalence of PR was 2.8% of all inflammatory arthritis. 8 In the Azar cohort, we reported the prevalence of PR at 4 in 1000 of general population. 9 Ansell and Bywaters suggested that in 10 to 15 percent of patients with RA, the disease began after a period of palindromic symptoms.10 In a recent report, RA was started as PR in 18% of patients.…”

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confidence: 99%

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Treatment of palindromic rheumatism: A systematic review

et al. 2021

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Palindromic rheumatism (PR) is an intermittent disease characterised by recurrent and self-resolving attacks of inflammation in the articular and peri-articular tissues. Attacks usually are monoarticular and last from a few hours to a few days. 1 During attacks, patients are asymptomatic. 1 Attacks mostly involve the knees, wrists, metacarpophalangeal joints and proximal interphalangeal (PIP) joints. 1 Finding autoantibodies associated with rheumatoid arthritis (RA) in a large percentage of patients with PR is an interesting feature of this disease. 2,3 In most reports, the frequency of positive rheumatoid factor (RF) and anticyclic citrullinated peptide (anti-CCP) in patients with PR is similar to RA. 2,3 Two recent studies reported two other autoantibodies, antimutated citrullinated vimentin (anti-MCV) in 70% and anticarbamylated protein/peptide antibodies (anti-CarP) in 24% of PR patients. 4,5 PR is an important disease despite the little attention paid to it. Firstly, PR is a relatively common disease. Pasero and Barbieri reported that the frequency of PR was 5% of RA. 6 Powel et al reported more prevalence of PR and concluded that for each of the

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Section: Introductionmentioning

confidence: 62%

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confidence: 99%

Treatment of palindromic rheumatism: A systematic review

et al. 2021

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“…• Online textbooks, didactic materials of indexed rheumatology journals, and frequently updated online educational hubs such as UpToDate serve as a foundation of online rheumatology education. • Online rheumatology education is enriched by peer review and social media activities, which are becoming major players in the time of the COVID- 19 pandemic.…”

Section: Key Pointsmentioning

confidence: 99%

“…Most resource-constrained countries have an enormous load of rheumatology patients and a vastly derisory number of trained rheumatologists [ 16 – 18 ]. Some countries like Korea and Iran have done well recently in the field of rheumatology education [ 19 , 20 ]. While countries like Mexico still face acute shortage of rheumatologists, others like Liberia have practically negligible trained rheumatologists [ 21 , 22 ].…”

Section: Current Barriers To Knowledge In Rheumatologymentioning

confidence: 99%

Moving towards online rheumatology education in the era of COVID-19

2020

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The coronavirus disease-2019 (COVID-19) pandemic has unsettled conventional medical education, hastening a switch to digital platforms and open-access publishing. Rheumatology is a fast evolving academic discipline that stands to gain by this switch. Most rheumatology textbooks are now available in digital formats, and these are complemented with live updating educational hubs such as UpToDate and ClinicalKey. Emerging topics of COVID-19 on these proprietary platforms are now freely available to all specialists. Social media channels, particularly Twitter, are becoming major players in the era of COVID-19 by offering online journal clubs, enabling fast dissemination of influential articles, and facilitating interactive education. Indexed rheumatology journals, in turn, aid online education by opening access to recommendations and other materials that are rapidly changing research and practice worldwide. Research peer review additionally offers learning experience to novice and seasoned researchers and authors. Global rheumatology societies have online learning resources, which are changing their format and geographic reach to meet the changing needs in the times of pandemic. While online teaching lacks emotional connections between mentors and mentees, switch to a more interactive format of education and regular contacts may partly solve the issue. Rheumatologists can take the lead in these challenging times and contribute more to online scholarly activities which are aimed to maintain and enrich education.

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Clinical Significance of Anti-Modified Citrullinated Vimentin Antibodies in Palindromic Rheumatism

Mahdavi

Rashtchizadeh

Khaknejad

et al. 2020

Laboratory Medicine

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Objective This study evaluated anti-modified citrullinated vimentin (anti-MCV) performance in determining the clinical picture and outcomes of palindromic rheumatism (PR). Methods In a retrospective study, patients with PR with at least 1 year of follow-up diagnosed according to clinical criteria were enrolled. Anti-MCV antibodies were measured, and levels >20 IU/mL were considered positive. Disease prognosis was assessed according to patients acquiring remission and preventing PR from developing into rheumatoid arthritis (RA) or other diseases. Results Seventy-six patients with PR with a mean follow-up of 30.57 months (median = 21 months; minimum = 12 months; maximum = 48 months) were included in the study. Anti-MCV antibodies were positive in 69.7% of patients. Metacarpophalangeal (MCP) joint involvement and positive anti-cyclic citrullinated peptides were significantly higher in patients who were anti-MCV-positive, whereas ankle joint involvement was significantly lower. No significant correlation was observed between the anti-MCV titer and the severity of attacks. Remission in patients who were anti-MCV-positive and negative was 75.5% and 78.3%, respectively, with no significant difference. Evolution to RA was observed in only 3.8% of patients who were anti-MCV-positive. No patients who were anti-MCV-negative developed RA. Conclusion Except for MCP and ankle joint involvement, anti-MCV was not helpful in determining the clinical picture and outcome of PR.

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Rheumatology training and research in Iran

Cited by 4 publications

References 75 publications

Treatment of palindromic rheumatism: A systematic review

Treatment of palindromic rheumatism: A systematic review

Moving towards online rheumatology education in the era of COVID-19

Clinical Significance of Anti-Modified Citrullinated Vimentin Antibodies in Palindromic Rheumatism

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