Rhino-orbital cerebral mucormycosis in a child with type 1 diabetes: A case report

Masmoudi, Mohamed; Hasnaoui, Mehdi; Abdeljalil, Nouha Ben; Guizani, Rihab; Lahmar, Rihab; Jaoued, Oussema; Rassas, Ahmed; Mighri, Khalifa

doi:10.1177/2050313x211036781

Cited by 2 publications

(2 citation statements)

References 15 publications

(51 reference statements)

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“…According to Jones et al (1993), patients with uncontrolled diabetes, malignancies, leukemia, glucocorticoid therapy, immunosuppressive therapy, malnutrition, and AIDS are at greater risk for mucormycosis [ 4 ]. The primary risk factors for this fungal infection in the pediatric population are hematopoietic stem cell transplantation, solid organ transplantation, and hematological malignancies (46%) [ 5 ]. Our patient, diagnosed with juvenile type 1 diabetes, suffered from mucormycosis of the maxilla.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Maxillary Mucormycosis in a Child With Juvenile Diabetes Mellitus

Sonpal,

Mundada,

Bhola

et al. 2024

Cureus

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Mucor and Rhizopus species are recognized as the primary culprits responsible for mucormycosis, a severe fungal infection known for its opportunistic nature. This infection primarily targets individuals with compromised immune systems, including those with diabetes mellitus and patients undergoing glucocorticoid therapy, where the immune response is weakened. This article aims to underscore the pivotal role of prompt diagnosis and intensive treatment in managing mucormycosis, particularly in pediatric patients, as it can avert death and mitigate serious morbidity. This case report emphasizes the urgency of identifying fungal infections in patients with diabetes early on and subsequently treating them aggressively to prevent adverse outcomes. It highlights the potential for excellent treatment outcomes when mucormycosis is promptly diagnosed and managed with intensive therapy. By doing so, significant morbidity and mortality associated with this condition can be effectively prevented, underscoring the importance of vigilance and proactive management in patients with predisposing factors for fungal infections.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Maxillary Mucormycosis in a Child With Juvenile Diabetes Mellitus

Sonpal,

Mundada,

Bhola

et al. 2024

Cureus

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“…For example, intestinal infections have been reported in neonates ( Sarin, 2010 ). In addition, cerebral rhino-orbital form has been described in children with comorbidities ( Amanati et al, 2021 ; Masmoudi et al, 2021 ). The male-to-female ratio is about 2.2:1, with slight variations between reports (Song et al; Jeong et al, 2019 ; Patel et al, 2020 ; Gupta and Ahuja, 2021 ).…”

Section: Difference Between Risk Factors and Affected Populations In ...mentioning

confidence: 99%

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

Acosta-España

Voigt

2022

Front. Microbiol.

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Fungal diseases were underestimated for many years. And the global burden of fungal infections is substantial and has increased in recent years. Invasive fungal infections have been linked to several risk factors in humans which basically depend on the individual homeostasis of the patients. However, many fungi can infect even apparently healthy people. Knowledge of these pathogens is critical in reducing or stopping morbidity and/or mortality statistics due to fungal pathogens. Successful therapeutic strategies rely on rapid diagnosis of the causative fungal agent and the underlying disease. However, the terminology of the diseases was updated to existing phylogenetic classifications and led to confusion in the definition of mucormycosis, conidiobolomycosis, and basidiobolomycosis, which were previously grouped under the now-uncommon term zygomycosis. Therefore, the ecological, taxonomic, clinical, and diagnostic differences are addressed to optimize the understanding and definition of these diseases. The term “coenocytic hyphomycosis” is proposed to summarize all fungal infections caused by Mucorales and species of Basidiobolus and Conidiobolus.

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Rhino-orbital cerebral mucormycosis in a child with type 1 diabetes: A case report

Cited by 2 publications

References 15 publications

A Rare Case of Maxillary Mucormycosis in a Child With Juvenile Diabetes Mellitus

A Rare Case of Maxillary Mucormycosis in a Child With Juvenile Diabetes Mellitus

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

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