Rhinocerebral mucormycosis: A report of two cases

Mucormycosis is an opportunistic fulminant fungal infection that can cause significant morbidity and frequent mortality in susceptible patients. Common predisposing factors include diabetes mellitus and immunosuppression. Even though this fungus is ubiquitous, the immune system usually prevents the disease, and it is rare. But in the present pandemic era, Mucormycosis has become a prevalent disease among immunocompromised patients and individuals with systemic pathosis. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The fungus invades the arteries leading to thrombosis that subsequently causes tissue necrosis. The infection can spread to orbital and intracranial structures by direct invasion of blood vessels. Here, we describe an interesting and rare case of sino-nasal mucormycosis in a seropositive, uncontrolled diabetic and suspected Covid positive individual to emphasize early diagnosis and treatment of this fatal fungal infection.

show abstract

Mucormycosis in HIV Positive Diabetic Individual Amid Covidien Epoch - A Rare Case Report

Waghmare

Banerjee

Pinto

et al. 2022

Journal of Indian Academy of Oral Medicine and Radiology

View full text Add to dashboard Cite

show abstract

Mucormycosis of jaws – literature review and current treatment protocols

Dewan

Patel

Pandya

et al. 2022

National Journal of Maxillofacial Surgery

View full text Add to dashboard Cite

Mucormycosis is a modern-day lifestyle disease that has burst into the health-care scenario. It is an opportunistic fungal infection that proliferates into the immunocompromised host by invasion of the fungus into the paranasal sinuses, thereby invading the palate, maxilla, and orbit. Left untreated it invades the cranial components such as cavernous sinus, skull base, and brain. Mucormycosis invades blood vessels, making these infections highly angioinvasive. We reviewed 45 cases of mucormycois of the head-and-neck region from 2010 to 2020 on the basis of electronic search peer-reviewed journals in Medline (PubMed) database. Presenting symptoms, risk factors, history of extraction, and treatment were tabulated and the data were analyzed. The mean age of patients was 53.8 years. 73.93% of patients had diabetes mellitus, 13.63% of patients had no immunocompromised state, and 8.74% of patients had other medical disorders. About 34.78% of cases had a history of extraction prior to manifestation of symptoms. Mucormycosis remains difficult to treat disease with a high mortality rate. At present, the triad of clinician's awareness, appropriate antifungal therapy, and aggressive surgical intervention represents treatment protocols against the disease.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Rhinocerebral mucormycosis: A report of two cases

Cited by 2 publications

References 0 publications

Mucormycosis in HIV Positive Diabetic Individual Amid Covidien Epoch - A Rare Case Report

Mucormycosis in HIV Positive Diabetic Individual Amid Covidien Epoch - A Rare Case Report

Mucormycosis of jaws – literature review and current treatment protocols

Contact Info

Product

Resources

About