Abstract:Rhinosporidiosis is a rare infection caused by Rhinosporidium seeberi, an organism classified in its own class, mesomycetozoea. It commonly affects mucus membranes namely the nasal mucosa, pharynx and the conjunctiva. We present the case of an 8-year-old female who presented with a flat, red, vascular, fleshy, pedunculated mass arising from the tarsal conjunctiva of the right upper eyelid. The mass was completely excised. On histopathological examination, multiple sporangia were seen in various stages of degen… Show more
“…4). The time of lesion evolution varies between 3 months and 1 year [16, 19, 22, 24, 30] with an average of 9 ± 5.09 months, a time relatively close to that found in the sample, which had an average evolution of symptoms around 18.6 months. Fig.…”
Section: Discussionsupporting
confidence: 54%
“…In the histopathological examination, R. seeberi is observed at all stages of development, and it is not possible to correlate some specific form of evolutionary stage with clinical presentation [34]. The literature describes some histological findings associated with infection, citing squamous metaplasia and epithelial hyperplasia [9, 19, 25].…”
Section: Discussionmentioning
confidence: 99%
“…Clinically, oculosporidiosis appears as a friable polypoid mass, causing a foreign body sensation, with irritation and watering from the eye, and with no effects on visual acuity according to some isolated case reports [3, 16, 19, 20].…”
BackgroundOculosporidiosis (ocular rhinosporidiosis) accounts for 15% of cases of rhinosporidiosis, which is a chronic granulomatous disease and is endemic in India and Sri Lanka. In Brazil, the climatic and hydrographic similarities to these endemic areas and the presence of riverside populations contributes to an increase in the incidence of rhinosporidiosis particularly in the State of Maranhão. This study, therefore, aimed to identify the number of diagnosed cases of oculosporidiosis and describe its the clinical epidemiology, laboratory, histopathology, and therapeutic characteristics.MethodsThe study is descriptive, observational, and cross-sectional, and reports the prevalence and clinical epidemiological characteristics of oculosporidiosis in the State of Maranhão, Brazil. A retrospective analysis of the paper and electronic records for a period from 1999 to 2017 was conducted in the University Hospital of Federal University of Maranhão (HU-UFMA), located in the northeastern region of Brazil.ResultsThirty patients were diagnosed with rhinosporidiosis, eight of them had oculosporidiosis and seven of these met the criteria to be included in the study. Of the cases (23.3% of all 30), five were men (71.4%) and two women (28.5%), with an average age of 16.4 ± 15.6 years. In terms of race, four patients (57.1%) declared themselves white and three (42.9%) as brown. The north of the state, the mesoregion, had the most diagnosed cases accounting for 57.1% of the total. Left eye was the most affected site, reported in six patients (85.7%), while the conjunctiva was affected in all patients. Rhinosporidiosis and papilloma were the predominant diagnostic hypotheses (28.5 and 28.5%, respectively), followed by chronic scleritis, granuloma, and chalazion (14.25, 14.25, and 14.25%, respectively). All these cases were treated with lesion excision, and only two patients (28.5%) progressed with recurrence.ConclusionIt was verified that there was a male predominance, with only one eye reported as an infected site, with no bilateral involvement. The younger age group (between 1 and 2 years of age) was more affected by oculosporidiosis, and histopathological examination was necessary for a conclusive diagnosis.
“…4). The time of lesion evolution varies between 3 months and 1 year [16, 19, 22, 24, 30] with an average of 9 ± 5.09 months, a time relatively close to that found in the sample, which had an average evolution of symptoms around 18.6 months. Fig.…”
Section: Discussionsupporting
confidence: 54%
“…In the histopathological examination, R. seeberi is observed at all stages of development, and it is not possible to correlate some specific form of evolutionary stage with clinical presentation [34]. The literature describes some histological findings associated with infection, citing squamous metaplasia and epithelial hyperplasia [9, 19, 25].…”
Section: Discussionmentioning
confidence: 99%
“…Clinically, oculosporidiosis appears as a friable polypoid mass, causing a foreign body sensation, with irritation and watering from the eye, and with no effects on visual acuity according to some isolated case reports [3, 16, 19, 20].…”
BackgroundOculosporidiosis (ocular rhinosporidiosis) accounts for 15% of cases of rhinosporidiosis, which is a chronic granulomatous disease and is endemic in India and Sri Lanka. In Brazil, the climatic and hydrographic similarities to these endemic areas and the presence of riverside populations contributes to an increase in the incidence of rhinosporidiosis particularly in the State of Maranhão. This study, therefore, aimed to identify the number of diagnosed cases of oculosporidiosis and describe its the clinical epidemiology, laboratory, histopathology, and therapeutic characteristics.MethodsThe study is descriptive, observational, and cross-sectional, and reports the prevalence and clinical epidemiological characteristics of oculosporidiosis in the State of Maranhão, Brazil. A retrospective analysis of the paper and electronic records for a period from 1999 to 2017 was conducted in the University Hospital of Federal University of Maranhão (HU-UFMA), located in the northeastern region of Brazil.ResultsThirty patients were diagnosed with rhinosporidiosis, eight of them had oculosporidiosis and seven of these met the criteria to be included in the study. Of the cases (23.3% of all 30), five were men (71.4%) and two women (28.5%), with an average age of 16.4 ± 15.6 years. In terms of race, four patients (57.1%) declared themselves white and three (42.9%) as brown. The north of the state, the mesoregion, had the most diagnosed cases accounting for 57.1% of the total. Left eye was the most affected site, reported in six patients (85.7%), while the conjunctiva was affected in all patients. Rhinosporidiosis and papilloma were the predominant diagnostic hypotheses (28.5 and 28.5%, respectively), followed by chronic scleritis, granuloma, and chalazion (14.25, 14.25, and 14.25%, respectively). All these cases were treated with lesion excision, and only two patients (28.5%) progressed with recurrence.ConclusionIt was verified that there was a male predominance, with only one eye reported as an infected site, with no bilateral involvement. The younger age group (between 1 and 2 years of age) was more affected by oculosporidiosis, and histopathological examination was necessary for a conclusive diagnosis.
“…Kuriakose ET described the clinical features of the lacrimal sac oculosporidiosis, as it may present with a painless, soft, swelling in the lower eyelid; which is fluctuating to the touch; there may be a history of bleeding from the nose, and haemolacria is seldom completely obstructed. 8 In our case, though there was no bleeding from the nose, other features were present. But still, we missed the diagnosis because isolated oculosporidiosis of the lacrimal sac is very rare.…”
Section: Discussionmentioning
confidence: 42%
“…7 Clinically, oculosporidiosis appears as a friable polypoid mass, causing a foreign body sensation, irritation and watering from the eye, and no effects on vision according to fewer case reports. 8 Oculosporidiosis commonly occurs in young and younger adults (15-40 years) with a predominance in males. 9 Here, we present an interesting case of oculosporidiosis.…”
Rhinosporidiosis is a chronic localized granulomatous disease caused by Rhinosporidium seeberi, an aquatic protistan parasite belonging to a clade, Mesomycetozoea. Infestation of Rhinosporidiosis on the eye and adnexa is termed oculosporidiosis. In such cases, conjunctival mucosa is mostly involved. Our case was a 25 years old male, presented with swelling of the lacrimal sac and deeper periorbital tissue and was presented as a case of orbital mass. Complete surgical excision of the lesion was done and Histopathological examination confirms orbital rhinosporidiosis. Postoperatively dapsone therapy was given for 6 months and the patient responded very well with no recurrence during the 6 months follow-up period.
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