Abstract:1Human rhinoviruses express 2 cysteine proteases, 2A and 3C, that are responsible for 2 viral polyprotein processing. Both proteases also suppress host gene expression by 3 inhibiting mRNA transcription, nuclear export and cap-dependent translation. 4However, the relative contribution that each makes in achieving this goal remains 5
Methods 83Cell lines and reagents 84 293T cells were maintained at 37°C in a 5% CO2 incubator with DMEM (Invitrogen, 85Fisher Scientific UK Ltd, Loughborough, UK) supplemented with… Show more
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