RhoA/ROCK-TAZ Axis regulates bone formation within calvarial trans-sutural distraction osteogenesis

Ye, Junjie; Wang, Jialu; Zhao, Jing; Xia, Meng; Wang, Hua; Sun, Lian; Zhang, Wei-Bing

doi:10.1016/j.cellsig.2024.111300

Cellular Signalling

2024

DOI: 10.1016/j.cellsig.2024.111300

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RhoA/ROCK-TAZ Axis regulates bone formation within calvarial trans-sutural distraction osteogenesis

Junjie Ye,

Jialu Wang,

Jing Zhao

et al.

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Cited by 2 publications

References 44 publications

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3D-printed manganese dioxide incorporated scaffold promotes osteogenic-angiogenic coupling for refractory bone defect by remodeling osteo-regenerative microenvironment

Yang,

Yao,

Sun

et al. 2025

Bioactive Materials

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3D-printed manganese dioxide incorporated scaffold promotes osteogenic-angiogenic coupling for refractory bone defect by remodeling osteo-regenerative microenvironment

Yang,

Yao,

Sun

et al. 2025

Bioactive Materials

View full text Add to dashboard Cite

Unraveling the Bone–Brain Axis: A New Frontier in Parkinson’s Disease Research

Liu,

Wu,

et al. 2024

IJMS

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Parkinson’s disease (PD), as a widespread neurodegenerative disorder, significantly impacts patients’ quality of life. Its primary symptoms include motor disturbances, tremor, muscle stiffness, and balance disorders. In recent years, with the advancement of research, the concept of the bone–brain axis has gradually become a focal point in the field of PD research. The bone–brain axis refers to the interactions and connections between the skeletal system and the central nervous system (CNS), playing a crucial role in the pathogenesis and pathological processes of PD. The purpose of this review is to comprehensively and deeply explore the bone–brain axis in PD, covering various aspects such as the complex relationship between bone metabolism and PD, the key roles of neurotransmitters and hormones in the bone–brain axis, the role of inflammation and immunity, microRNA (miRNA) functional regulation, and potential therapeutic strategies. Through a comprehensive analysis and in-depth discussion of numerous research findings, this review aims to provide a solid theoretical foundation for a deeper understanding of the pathogenesis of PD and to offer strong support for the development of new treatment methods.

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RhoA/ROCK-TAZ Axis regulates bone formation within calvarial trans-sutural distraction osteogenesis

Cited by 2 publications

References 44 publications

3D-printed manganese dioxide incorporated scaffold promotes osteogenic-angiogenic coupling for refractory bone defect by remodeling osteo-regenerative microenvironment

3D-printed manganese dioxide incorporated scaffold promotes osteogenic-angiogenic coupling for refractory bone defect by remodeling osteo-regenerative microenvironment

Unraveling the Bone–Brain Axis: A New Frontier in Parkinson’s Disease Research

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