Rhodium‐ and Platinum‐Catalyzed [4+3] Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta[b]indoles

Zinc‐Catalyzed [4+3] Cycloaddition with Concomitant Furan Annulation: Formation of Cyclohepta[b]Furans

“…Due to the convenience and efficiency in organic synthesis, tandem cyclizations have been studied with great depth in recent years. In 2013, a tandem cyclization to achieve cyclohepta[ b ]indoles was disclosed by Tang and his colleagues 8. In this report, the seven‐membered‐ring‐fused indole was synthesized involving a synchronous formation of indole.…”

Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations

“…[17] Cyclohepta[ b ]indole is present in a number of natural products [18] and bioactive pharmaceutical agents. [19] …”

Rhodium‐Catalyzed Tandem Cyclization/SiC Activation Reaction for the Synthesis of Siloles

“…Briefly, we anticipated that the intramolecular cyclization [15] of the aniline derivative 1 would generate such an organometallic intermediate (A). At the heart of this design is the new strategy to generate a MÀC(sp 2 ) species capable of SiÀC bond activation, which is distinct from the previous transmetalation or oxidative insertion pathways (Scheme 1).…”

“…At the heart of this design is the new strategy to generate a MÀC(sp 2 ) species capable of SiÀC bond activation, which is distinct from the previous transmetalation or oxidative insertion pathways (Scheme 1). Briefly, we anticipated that the intramolecular cyclization [15] of the aniline derivative 1 would generate such an organometallic intermediate (A). Subsequent selective activation of the SiÀC(sp 3 ) bond would provide the desired indole [3,2-b] silole 2.…”