Rhythmic and Light-Inducible Appearance of Clock-Associated Pseudo-Response Regulator Protein PRR9 through Programmed Degradation in the Dark in Arabidopsis thaliana

Ito, S.; Nakamichi, Norihito; Kiba, T.; Yamashino, T.; Mizuno, Toshiro

doi:10.1093/pcp/pcm169

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Messengers such as Ca 2+ and calmodulin signalling may also affect circadian regulation in response to light (Johnson et al, ; Millar & Kay, ). Light also directly controls the degradation of PRR5, PRR7, PRR9, TOC1, and GI proteins (Farré & Kay, ; Ito, Nakamichi, Kiba, Yamashino, & Mizuno, ; Kiba, Henriques, Hitoshi, & Chua, ; Más et al, ; Matsushika, Makino, Kojima, & Mizuno, ). These degradation events then act on outputs within a diurnal context, which change in duration throughout the season (Davis, ; Guerriero et al, ; Salazar et al, ; Song et al, ; Troein, Locke, Turner, & Millar, ).…”

Section: How Are Different Wavelengths Of Light Input To the Arabidopmentioning

confidence: 99%

Shining a light on the Arabidopsis circadian clock

Oakenfull

Davis

2017

Plant Cell & Environment

127

View full text Add to dashboard Cite

The circadian clock provides essential timing information to ensure optimal growth to prevailing external environmental conditions. A major time-setting mechanism (zeitgeber) in clock synchronization is light. Differing light wavelengths, intensities, and photoperiodic duration are processed for the clock-setting mechanism. Many studies on light-input pathways to the clock have focused on Arabidopsis thaliana. Photoreceptors are specific chromic proteins that detect light signals and transmit this information to the central circadian oscillator through a number of different signalling mechanisms. The most well-characterized clock-mediating photoreceptors are cryptochromes and phytochromes, detecting blue, red, and far-red wavelengths of light. Ultraviolet and shaded light are also processed signals to the oscillator. Notably, the clock reciprocally generates rhythms of photoreceptor action leading to so-called gating of light responses. Intermediate proteins, such as Phytochrome interacting factors (PIFs), constitutive photomorphogenic 1 (COP1) and EARLY FLOWERING 3 (ELF3), have been established in signalling pathways downstream of photoreceptor activation. However, the precise details for these signalling mechanisms are not fully established. This review highlights both historical and recent efforts made to understand overall light input to the oscillator, first looking at how each wavelength of light is detected, this is then related to known input mechanisms and their interactions.

show abstract

Section: How Are Different Wavelengths Of Light Input To the Arabidopmentioning

confidence: 99%

Shining a light on the Arabidopsis circadian clock

Oakenfull

Davis

2017

Plant Cell & Environment

127

View full text Add to dashboard Cite

show abstract

“…Overexpression of PRR5 slightly affects the peak time of some PRRs under LDs, but mutations in PRR genes do not affect the peak time of expression of other PRRs under these conditions (Appendix Fig S4A and B). These proteins are degraded during the night, so they mainly accumulate during the day when CO protein also accumulates (Mas et al, 2003b;Farré & Kay, 2007;Ito et al, 2007;Kiba et al, 2007). Through this regulation, PRRs allow detection of long-light periods and contribute to recognition of LDs, interacting with and stabilizing CO protein during the day specifically under LDs.…”

Section: Prrs Participate In Light Signaling That Mediates Photoperiomentioning

confidence: 99%

“…The abundance of their transcripts and proteins exhibit circadian rhythms, and under diurnal conditions, they peak in expression sequentially at 2-3 h intervals during the light period in the order PRR9, PRR7, PRR5, PRR3, and TOC1 (Matsushika et al, 2000;Fujiwara et al, 2008). PRR9, PRR7, PRR5, and TOC1 proteins are degraded during the night, so they mainly accumulate during the day when they repress transcription of genes encoding other clock components such as LATE ELONGATED HYPOCOTYL (LHY) and CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) (Mas et al, 2003b;Farré & Kay, 2007;Ito et al, 2007;Kiba et al, 2007;Nakamichi et al, 2010;Huang et al, 2012). Mutations in the PRR genes also delay flowering under LDs (Nakamichi et al, 2005;Ito et al, 2008), but double or triple mutants exhibit much stronger phenotypes suggesting functional redundancy between the genes (Nakamichi et al, 2005, p. 549;Ito et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

PSEUDO RESPONSE REGULATORs stabilize CONSTANS protein to promote flowering in response to day length

et al. 2017

View full text Add to dashboard Cite

Seasonal reproduction in many organisms requires detection of day length. This is achieved by integrating information on the light environment with an internal photoperiodic time‐keeping mechanism. Arabidopsis thaliana promotes flowering in response to long days (LDs), and CONSTANS (CO) transcription factor represents a photoperiodic timer whose stability is higher when plants are exposed to light under LDs. Here, we show that PSEUDO RESPONSE REGULATOR (PRR) proteins directly mediate this stabilization. PRRs interact with and stabilize CO at specific times during the day, thereby mediating its accumulation under LDs. PRR‐mediated stabilization increases binding of CO to the promoter of FLOWERING LOCUS T (FT), leading to enhanced FT transcription and early flowering under these conditions. PRRs were previously reported to contribute to timekeeping by regulating CO transcription through their roles in the circadian clock. We propose an additional role for PRRs in which they act upon CO protein to promote flowering, directly coupling information on light exposure to the timekeeper and allowing recognition of LDs.

show abstract

“…Thus, TOC1 degradation is the result of a complex interplay among TOC1, ZTL, GI and PRR3. Other clock components such as LHY [58], PRR7 [59], PRR9 [60] and GI [61] are also subject to proteasomal degradation. Whereas the stability of GI appears to be regulated by a RING-type E3-ubiquitin-ligase during the night [62], mechanisms for the other proteins are still unknown.…”

Section: Regulated Protein Turnover Within the Circadian Oscillatormentioning

confidence: 99%

An expanding universe of circadian networks in higher plants

Pruneda‐Paz

Kay

2010

Trends in Plant Science

165

138

View full text Add to dashboard Cite

Extensive circadian clock networks regulate almost every biological process in plants. Clockcontrolled physiological responses are coupled with daily oscillations in environmental conditions resulting in enhanced fitness and growth vigor. Identification of core clock components and their associated molecular interactions has established the basic network architecture of plant clocks, which consists of multiple interlocked feedback loops. A hierarchical structure of transcriptional feedback overlaid with regulated protein turnover sets the pace of the clock and ultimately drives all clock-controlled processes. While originally described as linear entities, increasing evidence suggests that many signaling pathways can act as both inputs and outputs within the overall network. Future studies will determine the molecular mechanisms involved in these complex regulatory loops. The circadian clockThe circadian clock is an endogenous mechanism that allows an organism to coordinate the temporal organization of biological processes to specific times of the day or night. Clock function is widely distributed among species since most organisms adapted their physiology and behavior to the periodic oscillations in external signals that take place throughout each diurnal cycle [1,2]. These signals entrain or set the pace of the clock, which in turn has the capacity to drive self-sustained oscillations with a period ~ 24 hours [1,2]. Clock-generated biological rhythms allow an organism to anticipate the onset of environmental changes providing an adaptive advantage that result in increased fitness and survival [3][4][5].Because of their non-motile nature, plants strongly rely on the ability to interact with their environment. The circadian clock provides a critical mechanism that integrates multiple external signals and adjusts plant physiological responses accordingly. Indeed, the pervasiveness of the clock extends to nearly every aspect of plant growth and development [6][7][8]. In this article we review recent progress on the mechanisms underlying clock function in plants. The accumulated data point to an expansive regulatory network that integrates in a reciprocal fashion with many major signaling modules. Transcriptional circuits within the circadian oscillatorIn most organisms studied to date, the circadian clock is proposed to function as a biochemical oscillator built on multiple interlocked regulatory loops [1,2,9,10]. Despite this common architecture, specific clock components and biochemical processes are encountered among © 2010 Elsevier Ltd. All rights reserved.Corresponding author: Kay, S.A. (skay@ucsd.edu). Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered wh...

show abstract

Rhythmic and Light-Inducible Appearance of Clock-Associated Pseudo-Response Regulator Protein PRR9 through Programmed Degradation in the Dark in Arabidopsis thaliana

Cited by 4 publications

References 0 publications

Shining a light on the Arabidopsis circadian clock

Shining a light on the Arabidopsis circadian clock

PSEUDO RESPONSE REGULATORs stabilize CONSTANS protein to promote flowering in response to day length

An expanding universe of circadian networks in higher plants

Contact Info

Product

Resources

About