Rhythmologische und metabolische Kontrolle

Guckel, Denise; Sohns, Christian; Sommer, Philipp

doi:10.1007/s00059-022-05128-4

Cited by 2 publications

(1 citation statement)

References 53 publications

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“…Diabetes mellitus is a well-established risk factor for arrhythmias [ 59 – 61 ]. The pathophysiology of diabetes mellitus-related arrhythmias is not fully understood; however, it is related to not only structural, electrical, electromechanical, autonomic remodeling but also oxidative stress and inflammation [ 62 – 64 ].…”

Section: Discussionmentioning

confidence: 99%

Factors associated with complications in ST-elevation myocardial infarction: a single-center experience

Mavungu Mbuku,

Mukombola Kasongo,

Goube

et al. 2023

BMC Cardiovasc Disord

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Background ST-elevation myocardial infarction (STEMI) is a major public health problem. This study aimed to determine the prevalence and identify the determinants of STEMI-related complications in the Cardiology Intensive Care Unit of the Sud Francilien Hospital Center (SFHC). Methods We retrospectively analyzed the data of 315 patients with STEMI aged ≥ 18 years. Logistic regression was used to identify factors independently associated with the occurrence of complications. Results Overall, 315 patients aged 61.7 ± 13.4 years, of whom 261 were men, had STEMI during the study period. The hospital frequency of STEMI was 12.7%. Arrhythmias and acute heart failure were the main complications. Age ≥ 75 years (adjusted odds ratio [aOR], 5.18; 95% confidence interval [CI], 3.92–8.75), hypertension (aOR, 3.38; 95% CI, 1.68–5.82), and cigarette smoking (aOR, 3.52; 95% CI, 1.69–7.33) were independent determinants of acute heart failure. Meanwhile, diabetes mellitus (aOR, 1.74; 95% CI, 1.09–3.37), history of atrial fibrillation (aOR, 2.79; 95% CI, 1.66–4.76), history of stroke or transient ischemic attack (aOR, 1.99; 95% CI, 1.31–2.89), and low high-density lipoprotein-cholesterol (HDL-C) levels (aOR, 3.70; 95% CI, 1.08–6.64) were independent determinants of arrhythmias. Conclusion STEMI is a frequent condition at SFHC and is often complicated by acute heart failure and arrhythmias. Patients aged ≥ 75 years, those with hypertension or diabetes mellitus, smokers, those with a history of atrial fibrillation or stroke, and those with low HDL-C levels require careful monitoring for the early diagnosis and management of these complications.

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