IntroductionThe results of previous studies have shown that in girls with right convex thoracic adolescent idiopathic scoliosis (IS) there is significantly increased vascularity of the left breast as compared with the right one [10]. It has also been found that in deceased women with right convex thoracic IS, the mean length of the ribs corresponding to the apical and the two periapical vertebrae was greater on the concave than on the convex side [11]. These changes were ascribed to disturbed sympathetic function. Indeed, in growing rabbits stimulation of the longitudinal rib growth by unilateral resection of intercostal nerves, including the sympathetic fibres, resulted in hyperaemia of the denervated anterior hemithorax [1], increased longitudinal rib growth [2] and scoliosis with the convexity to the opposite side of the denervation and characteristics of IS in humans [3].The inter-related results of these and other clinical and experimental studies have provided evidence supporting the thoracospinal theory of the pathogenesis of IS. According to this new theory, stimulation of longitudinal growth of the left ribs is the origin of right convex IS in adolescent girls [15].In connection with these studies, experiments were also undertaken to investigate the possibility of correcting or suppressing the progression of scoliosis induced in rabbits.In a first experiment, scoliosis was induced by unilateral resection of three intercostal nerves on the left side in growing rabbits. Three months after the operation, all rabbits had developed scoliosis with a mean Cobb angle of 22.5°. The concavity of the curve was on the side of the denervation. At this time, one rib of the convexity, one, two, three or four spaces above the apical vertebra of the curve, after osteotomy, was mechanically elongated by 7 mm using a metallic expander. The initial scoliosis was corrected immediately after the operation, and remained unchanged 3 weeks later [14] (Fig. 1).In a second experiment, three intercostal nerves were resected on one side of the thorax in rabbits with a mean body weight of 350 g. Then the animals were allocated into three groups, with six rabbits in each. In the first group, used as reference, a progressive scoliosis developed in all animals, which 3 months after the operation averaged 27.0°. In the second group, group A, 1 month af-
AbstractThe results of previous clinical and experimental studies have provided accumulated evidence for the role of rib asymmetry in the pathogenesis of idiopathic scoliosis (IS). Moreover, it has been shown that scoliosis induced in rabbits can be corrected by elongation or growth stimulation of ribs on the side of the convexity. Taking these observations into consideration, a 7-year-old girl with right convex thoracolumbar IS was operated upon by 2-cm shortening of three concave ribs. The preoperative coronal Cobb angle was 46°and the sagittal angle was 55°. Twenty-seven months after the operation the curves were reduced to 21°a nd 35°, or by 54 and 36%, respectively. It is concluded ...