In this paper, we prove the nonexistence of stable integral currents in compact oriented warped product pointwise semi-slant submanifold Mn of a complex space form M˜(4ϵ) under extrinsic conditions which involve the Laplacian, the squared norm gradient of the warped function, and pointwise slant functions. We show that i-the homology groups of Mn are vanished. As applications of homology groups, we derive new topological sphere theorems for warped product pointwise semi-slant submanifold Mn, in which Mn is homeomorphic to a sphere Sn if n≥4 and if n=3, then M3 is homotopic to a sphere S3 under the assumption of extrinsic conditions. Moreover, the same results are generalized for CR-warped product submanifolds.