“Ricin syndrome”. A possible new teratogenic syndrome associated with ingestion of castor oil seed in early pregnancy: a case report

M, el Mauhoub; Mm, Khalifa; Ob, Jaswal; Ms, Garrah

doi:10.1080/02724936.1983.11748269

Cited by 13 publications

(2 citation statements)

References 16 publications

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“…El Mauhoub et al . ( 1983 ) report adverse neonatal events, such as moderate growth impairment, convulsions, craniofacial dysmorphia, limb reductions and vertebral defects, as being associated with the ingestion of castor oil during pregnancy. In a prospective evaluation study by Garry et al .…”

Section: Discussionmentioning

confidence: 99%

A systematic review: Are herbal and homeopathic remedies used during pregnancy safe?

Boltman-Binkowski

2016

curationis

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BackgroundHerbal and homeopathic remedies have been used to assist with childbearing and pregnancy for centuries. Allopathic (‘Western’) medicine is traditionally avoided during pregnancy because of limited drug trials and the suspected teratogenic effects of these medications. This has led to an increase in the use of herbal and homeopathic remedies, as they are viewed to have no teratogenic effect on the developing foetus. Health providers are faced with questions from their clients regarding the safety of these remedies, but much of the evidence about these herbal and homeopathic remedies is anecdotal and few remedies have been tested scientifically.ObjectivesBy conducting a systematic review, the primary objective was to evaluate maternal and neonatal outcomes of ingested herbal and homeopathic remedies during pregnancy.MethodA systematic review was conducted to synthesise all the evidence with the purpose of evaluating the safety of herbal and homeopathic remedies based on adverse maternal and neonatal outcomes. Only randomised and quasi-randomised controlled trials that met all inclusion criteria were included in the review.ResultsThe ingestion of ginger for nausea and vomiting during pregnancy was shown to have no harmful maternal or neonatal effects. Ingestion of castor oil for induction of labour showed a tendency towards an increase in the incidence of caesarean section and meconium-stained liquor, warranting further research into its safety issues.ConclusionLarger randomised controlled trials need to be conducted, especially in South Africa, to establish the safety and efficacy of commonly-used remedies.

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Section: Discussionmentioning

confidence: 99%

A systematic review: Are herbal and homeopathic remedies used during pregnancy safe?

Boltman-Binkowski

2016

curationis

View full text Add to dashboard Cite

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“…To our knowledge, no case of poisoning from this seed has yet been documented in the Kingdom of Saudi Arabia or any other Arab country. However, El Mauhoub et al 13 recently reported a possible teratogenic effect in a Libyan infant whose mother ingested castor oil seeds for 8 weeks in early pregnancy.…”

Section: Discussionmentioning

confidence: 99%