Rickettsiae in Ticks, Japan, 2007–2011

Gaowa,; Ohashi, Norio; Aochi, Minami; Wuritu,; Wu, Dongxing; Yoshikawa, Yuko; Kawamori, Fumihiko; Honda, Toshiro; Fujita, Hiromi; Takada, Nobuhiro; Oikawa, Yosaburo; Kawabata, Hiroki; Ando, Shuji; Kishimoto, Tadamitsu

doi:10.3201/eid1902.120856

Cited by 45 publications

(40 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of these, Rickettsia, Ehrlichia, Anaplasma, and Neoehrlichia are associated with ticks, and some cause febrile illnesses in humans as well as livestock; therefore, these genera are of significance to public and veterinary health. Recently, Anaplasma phagocytophilum infection and coinfection with Rickettsia japonica in humans have been confirmed in central to western parts of Japan (3,4), where infected ticks were present (5). In the past decade, tick-associated Rickettsiales bacteria have also been identified in wild mammals, including deer, boar, Japanese serows, field mice, and wild rats in Japan (2,(6)(7)(8)(9)(10)(11)(12)(13)(14).…”

mentioning

confidence: 99%

A Molecular and Serological Survey of Rickettsiales Bacteria in Wild Sika Deer (Cervus nippon nippon) in Shizuoka Prefecture, Japan: High Prevalence of Anaplasma Species

Wuritu

Yoshikawa

et al. 2015

Jpn J Infect Dis

Self Cite

View full text Add to dashboard Cite

SUMMARY:We surveyed Rickettsiales bacteria, including Rickettsia, Ehrlichia, Anaplasma, and Neoehrlichia, in wild sika deer (Cervus nippon nippon) from Shizuoka prefecture, Japan. In spleen samples from 187 deer, Anaplasma phagocytophilum (deer type), A. bovis, and A. centrale were successfully detected by PCR assay targeting to 16S rDNA or p44/msp2, and their positive rates were 96.3z (180/187), 53.5z (100/187), and 78.1z (146/187), respectively. Additionally, 2 or 3 Anaplasma species could be detected from a single deer in 165 spleen samples (88.2z), indicating dual or triple infection. In contrast, A. phagocytophilum (human type) 16S rDNA, Rickettsia gltA, Ehrlichia p28/omp-1, and Neoehrlichia 16S rDNA could not be amplified. The serological test of 105 deer serum samples by immunofluorescence assay showed that the detection of antibodies against antigens of A. phagocytophilum HZ (US-human isolate) and Rickettsia japonica YH were 29.5z (31/105) and 75.2z (79/105), respectively. These findings suggest that A. phagocytophilum (deer type), A. centrale, and A. bovis are highly dominant and prevalent in wild sika deer from Shizuoka, a central region of Japan, and that the antibodies against some Rickettsiales bacteria have also been retained in deer blood.

show abstract

mentioning

confidence: 99%

A Molecular and Serological Survey of Rickettsiales Bacteria in Wild Sika Deer (Cervus nippon nippon) in Shizuoka Prefecture, Japan: High Prevalence of Anaplasma Species

Wuritu

Yoshikawa

et al. 2015

Jpn J Infect Dis

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, we speculate that the general prevalence is even lower because we have never previously detected DNA from or isolated this Rickettsia sp. in Japan despite numerous epidemiological studies using ticks (Gaowa et al 2013). Although the prevalence is low, our study shows the diversity of Rickettsia spp.…”

Section: Discussionmentioning

confidence: 53%

“…It belongs to SFG phylogenetically and was recently associated with lesional skin inflammation in an afebrile human (Imaoka et al 2011). R. tamurae is more prevalent in Japan than R. japonica (Gaowa et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Isolation of the Rickettsial Agent Genetically Similar toCandidatusRickettsia kotlanii, fromHaemaphysalis megaspinosain Japan

Andoh

Ogasawara

Sakamoto

et al. 2014

Vector-Borne and Zoonotic Diseases

Self Cite

View full text Add to dashboard Cite

Two rickettsial isolates, HM-1 and HM-2, were isolated from Haemaphysalis megaspinosa collected in Japan in 2006 and 2011, respectively. The isolates were analyzed by DNA sequences of the outer membrane protein A gene, the outer membrane protein B gene, the citrate synthase gene, the genus Rickettsia-specific outer membrane protein 17-kDa gene, the 16S ribosome RNA gene, and the PS120 protein gene (

show abstract

“…To our knowledge, this is the first case of human anaplasmosis infection in the Inner Mongolia Autonomous Region. cedure described previously (9,10), and the results were all negative. For serological evidence, indirect immunofluorescence assay (IFA) using A. phagocytophilum HZ strain (US-human isolate) cultured with THP-1, HL60, and NB4 cells as antigens was performed using the procedure as described previously (2).…”

mentioning

confidence: 89%

Case of Human Infection with Anaplasma phagocytophilum in Inner Mongolia, China

et al. 2018

Self Cite

View full text Add to dashboard Cite

Rickettsiae in Ticks, Japan, 2007–2011

Cited by 45 publications

References 9 publications

A Molecular and Serological Survey of <i>Rickettsiales</i> Bacteria in Wild Sika Deer (<i>Cervus nippon nippon</i>) in Shizuoka Prefecture, Japan: High Prevalence of <i>Anaplasma</i> Species

A Molecular and Serological Survey of <i>Rickettsiales</i> Bacteria in Wild Sika Deer (<i>Cervus nippon nippon</i>) in Shizuoka Prefecture, Japan: High Prevalence of <i>Anaplasma</i> Species

Isolation of the Rickettsial Agent Genetically Similar toCandidatusRickettsia kotlanii, fromHaemaphysalis megaspinosain Japan

Case of Human Infection with <i>Anaplasma phagocytophilum</i> in Inner Mongolia, China

Contact Info

Product

Resources

About