Rickettsial infections: Past and present perspectives

Kamath, Vasantha; Ganguly, Shreyashi; Bhatia, Jasmine Kaur; Himabindu, R

doi:10.4103/ajim.ajim_22_19

Cited by 5 publications

(10 citation statements)

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“…malas condiciones de higiene, hacinamiento, manejo ineficiente de residuos en las viviendas, etc.) que interactúan entre sí para generar morbilidad y mortalidad con frecuencias y severidad variables (Kamath et al, 2020;Manrique-Saide, 2023).…”

Section: Aspectos Generales De Las Rickettsiosisunclassified

“…El cuadro clínico de las rickettsiosis, que se presenta después de un periodo de incubación de seis a 21 días, es de severidad variable dependiendo de la especie infectante, siendo R. rickettsii, la especie más patogénica y virulenta para el ser humano (Kamath et al, 2020). La mayor parte de las rickettsiosis (hasta el 70% de los casos) se caracterizan por la "tríada clásica": fiebre (100% de los casos), cefalea y exantema (Moreno-Trujillo et al, 2020) Trujillo et al, 2020).…”

Section: Aspectos Generales De Las Rickettsiosisunclassified

“…El género Rickettsia (familia Rickettsiaceae, orden Rickettsiales, subdivisión Alpha [] de las Proteobacterias) está integrado por bacterias, coloquialmente conocidas como rickettsias, de doble membrana, pleomorfas e intracelulares obligadas que viven y se reproducen en el citoplasma y/o el núcleo de diversas células eucariotas. Son pequeñas (0.3-0.5 μm por 0.8-2.0 μm) con envoltura de una bacteria Gram negativa y se dividen por fisión binaria (Kamath et al, 2020), por lo que, para su identificación formal, los métodos tradicionales usados en bacteriología no pueden ser aplicados por su baja sensibilidad (Parija, 2023). Se visualizan usando Giemsa (tiñen de rojo), coloración de Macchiavello o tinción de Giménez y utilizando técnicas de tinción directa de anticuerpos fluorescentes (Kamath et al, 2020).…”

Section: Género Rickettsia: Características Generales Y Molecularesunclassified

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Actualización Sobre Aspectos Epidemiológicos De La Rickettsiosis en El Trópico De México

Torres-Castro,

Reyes-Novelo,

Arroyo-Ramírez

et al. 2024

Trop Subtrop Agroecosyst

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Background: Rickettsioses are diseases caused by Rickettsia bacteria, transmitted through tick or mite bites, or through contact with feces from lice or fleas. In Mexico, these diseases are a major public health concern, particularly in the tropical states where they appear to be responsible for most cases and the highest mortality rates. In the epidemiology of rickettsiosis, domiciled dogs and rodents play a significant role in maintaining of biological vectors in the vicinity of dwellings and in domestic and companion animals that people live with. It has been determined that some characteristics of households in localities with some degree of social-economic marginalization increase the risk of occurrence of Rickettsia spp. in the occupants. Objective: To present a literature review on the epidemiology of rickettsiosis, delving into studies about the characteristics of the peridomiciliary space and the most common animals that live there involved in the occurrence of rickettsiosis in localities of the Mexican tropic. Methodology: Using keywords related to the objective, a search between November 2022 and April 2023 was carried out on digital sources of information from various types of scientific references. The search results were classified according to eligibility criteria. Results: The information generated in the Mexican tropic on the epidemiology of rickettsiosis involving synanthropic and domestic animals, as well as the characteristics of the peridomiciliary space, is more extensive and numerous than in other regions of the country. Implications: The present review includes part of the epidemiological panorama of endemic rickettsiosis in the Mexican tropics, which is not necessarily attributable to other regions where environmental and socioeconomic conditions can modify the behavior of these diseases. Conclusions: It has been documented that the transmission of zoonoses such as rickettsiosis is influenced by ecological or environmental conditions and the characteristics of anthropized environments such as the peridomicile, which represent factors related to the occurrence of these diseases in the households’ occupants of localities in the Mexican tropics. Several pathogenic species of Rickettsia are found in domesticated dogs and some species of wild and synanthropic rodents, indicating their significant epidemiological role in the tropical regions of Mexico.

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Section: Aspectos Generales De Las Rickettsiosisunclassified

Section: Género Rickettsia: Características Generales Y Molecularesunclassified

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Actualización Sobre Aspectos Epidemiológicos De La Rickettsiosis en El Trópico De México

Torres-Castro,

Reyes-Novelo,

Arroyo-Ramírez

et al. 2024

Trop Subtrop Agroecosyst

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“…They may turn gangrenous. 3 A pathognomic cutaneous manifestation of Rickettsial fever is an Eschar. The eschar forms after the bite of the vector.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous manifestations of Rickettsial fever in paediatric age group

Somashekar

Ravindra

2022

Int J Res Dermatol

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Background: Rickettsial fever is well known to have various cutaneous manifestations that can help in the probable clinical diagnosis especially in the context of non availability of resources and aid in prompt administration of treatment, hence reducing mortalitiy and morbidity. The main objective of this study was to estimate the prevalence of cutaneous manifestations in patients with a positive Weil-Felix and also to study the plethora of cutaneous manifestations seen in Rickettsial fever.Methods: All the consenting patients admitted in in the Department of Paediatrics below 18 years and with a positive Weil-Felix test were thoroughly screened for cutaneous manifestations.Results: Of the 114 patients screened, 29 children (21.05%) had cutaneous manifestations. The various cutaneous manifestations encountered in the study are erythematous rash, maculopapular rash, petechial rash and cutaneous necrosis.Conclusions: Though cutaneous manifestations was seen in only 21% of the patients with fever, when present it could help in suspecting rickettsial fever in a case of pyrexia of unknown origin.

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“…Local studies from North Karnataka (Vijayapura and Gadag), the centre of Karnataka (Shivamogga), and the southern part of rural Bangalore have reported rickettsial disease among adults and children 4,13,14,15 . This study was conducted because this region is surrounded by forest and the majority of the population is rural, relying on agriculture and farming for a living.…”

Section: Introductionmentioning

confidence: 99%

Assessment of rickettsial diseases presenting as acute undifferentiated febrile illness using clinical tools in a government tertiary care teaching hospital, Chamarajanagar, Karnataka

Jaikar

Divya

Ramesh

et al. 2022

ijhs

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Background: Rickettsial diseases are re-emerging in India. Acute undifferentiated febrile illness is a difficult case to treat (AUFI). The greatest problem for clinicians is the early diagnosis of these diseases when antibiotic therapy is most successful.To determine the prevalence of RDs, therapy outcomes, and socio-demographic factors associated with RDs in AUFI. Patients and Methods: Fever and/or clinical signs of Rickettsial infection in patients admitted to the CIMS teaching hospital in Chamarajanagar for four years. Purposive sampling found AUFI in 1638 people. The diagnosis of rickettsial disease relied on clinical features. The Weil-Felix test was one. Then came a 48–72-hour estimate of doxycycline response. Results:Out of 1810 AUFI cases, 198 (10.93%) were rickettsial, with 190 (95.95%) having an RGA score of 14 or more, and 18 (9.09%) having an RGA score of 14 or less. Males aged 30-40 were most affected. Leucopenia, thrombocytopenia, etc. were found. Doxycycline was effective in 151 (89.35%) of cases within one week of onset. The remaining 18 (10.65%) required longer-term doxycycline with other drugs, three had severe complications, and one died. RD prevalence 70.01 %. Enteric fever, Dengue fever, Chikungunya fever, and Rickettsial diseases were the most common diseases diagnosed in patients with undifferentiated febrile illness.

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Rickettsial infections: Past and present perspectives

Cited by 5 publications

References 0 publications

Actualización Sobre Aspectos Epidemiológicos De La Rickettsiosis en El Trópico De México

Actualización Sobre Aspectos Epidemiológicos De La Rickettsiosis en El Trópico De México

Cutaneous manifestations of Rickettsial fever in paediatric age group

Assessment of rickettsial diseases presenting as acute undifferentiated febrile illness using clinical tools in a government tertiary care teaching hospital, Chamarajanagar, Karnataka

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