Rickettsiosis Caused by Rickettsia parkeri, Mexico

Peniche-Lara, Gaspar; Lara-Perera, Victor

doi:10.3201/eid2802.210454

Cited by 10 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study presents the unusual presence of R. parkeri in synanthropic rodents ( M. musculus ) and domiciled dogs from a rural community in southeastern Mexico. These findings involve, for the first time M. musculus as accidental hosts in the epidemiological cycle of this Rickettsia species endemic to the study region (Peniche‐Lara & Lara‐Perera, 2022; Torres‐Castro, Sánchez‐Montes, et al, 2022), and the case of the dogs, they reinforce their participation in the said epidemiological cycle (Sánchez‐Montes et al, 2021) after the identification of this Rickettsia species in a domiciliated dog from the study region by Ojeda‐Chi et al (2019).…”

Section: Discussionmentioning

confidence: 84%

“…However, these ectoparasites have not been involved in the zoonotic transmission of R. parkeri . Recently, Peniche‐Lara and Lara‐Perera (2022) and Torres‐Castro, Sánchez‐Montes, et al (2022) reported the first cases of R. parkeri in symptomatic and asymptomatic inhabitants of Yucatán (southeastern Mexico). These records are relevant for public health because they show the circulation of this Rickettsia species among the inhabitants of Mexico (Sánchez‐Montes et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An unusual identification ofRickettsia parkeriin synanthropic rodents and domiciliated dogs of a rural community from Yucatán, Mexico

Arroyo‐Ramírez,

Lugo‐Caballero,

Panti‐May

et al. 2023

Zoonoses and Public Health

View full text Add to dashboard Cite

Rickettsia parkeri belongs to the spotted fever group (SFG) of the Rickettsia genus. This bacterium causes mild rickettsiosis in humans and is mainly transmitted by Amblyomma ticks. Its medical importance is emerging in the Americas, including Mexico. Synanthropic rodents and domiciled dogs participate as accidental hosts in epidemiological cycles of Rickettsia of the SFG. The aim is to report the presence of R. parkeri in synanthropic rodents and domiciled dogs from a rural community of Yucatán, Mexico. Rodents were captured, and plasma samples were taken from dogs in 48 households from Ucú, Yucatán, Mexico. A spleen sample (rodents) and plasma (dogs) were used in the propagation of Rickettsia on Vero cells. These infected cells were used in the extraction of genomic DNA. Rickettsia DNA was identified using a semi‐nested PCR (snPCR); some products were sent for sequencing. The recovered sequences were analysed with bioinformatics programs, and a phylogenetic tree was built to determine the Rickettsia species. One hundred animals were sampled: 36 synanthropic rodents and 64 dogs. The snPCR evidenced the presence of Rickettsia DNA in 10 rodents (10/36, 27.8%) and 18 dogs (18/64, 28.1%), which represents a global frequency of 28% (28/100) in this study. The bioinformatics analysis yielded homology to R. parkeri and was demonstrated in the phylogenetic tree. The first evidence of the presence of R. parkeri in synanthropic rodents (Mus musculus) from Mexico is presented; likewise, the participation of domestic dogs in the transmission cycle of this bacterium with potential importance in public health is confirmed.

show abstract

Section: Discussionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

An unusual identification ofRickettsia parkeriin synanthropic rodents and domiciliated dogs of a rural community from Yucatán, Mexico

Arroyo‐Ramírez,

Lugo‐Caballero,

Panti‐May

et al. 2023

Zoonoses and Public Health

View full text Add to dashboard Cite

show abstract

“…Across México, rickettsiae pathogens have been described in vectors and hosts in northern Baja California, Sonora, Chihuahua [19], Campeche [20,21], Yucatán [22], Tabasco [23], Veracruz [21,24], Tamaulipas [24][25][26], and Coahuila [4,12,27]. Ongoing outbreaks of RMSF since 2008, with high fatality rates, in northwestern regions of México have been much of the focused surveillance, with human disease also reported from adjacent indigenous communities of Arizona [28][29][30][31][32].…”

Section: Introductionmentioning

confidence: 99%

Brown Dog Tick (Rhipicephalus sanguineus Sensu Lato) Infection with Endosymbiont and Human Pathogenic Rickettsia spp., in Northeastern México

Salomon

Santos

Zecca

et al. 2022

IJERPH

View full text Add to dashboard Cite

Of the documented tick-borne diseases infecting humans in México, Rocky Mountain spotted fever (RMSF), caused by the Gram-negative bacterium Rickettsia rickettsii, is responsible for most fatalities. Given recent evidence of brown dog tick, Rhipicephalus sanguineus s.l., as an emerging vector of human RMSF, we aimed to evaluate dogs and their ticks for rickettsiae infections as an initial step in assessing the establishment of this pathosystem in a poorly studied region of northeastern México while evaluating the use of dogs as sentinels for transmission/human disease risk. We sampled owned dogs living in six disadvantaged neighborhoods of Reynosa, northeastern México to collect whole blood and ticks. Of 168 dogs assessed, tick infestation prevalence was 53%, composed of exclusively Rh. sanguineus s. l. (n = 2170 ticks). Using PCR and sequencing, we identified an overall rickettsiae infection prevalence of 4.1% (n = 12/292) in ticks, in which eight dogs harbored at least one infected tick. Rickettsiae infections included Rickettsia amblyommatis and Rickettsia parkeri, both of which are emerging human pathogens, as well as Candidatus Rickettsia andeanae. This is the first documentation of pathogenic Rickettsia species in Rh. sanguineus s.l. collected from dogs from northeastern México. Domestic dog infestation with Rickettsia-infected ticks indicates ongoing transmission; thus, humans are at risk for exposure, and this underscores the importance of public and veterinary health surveillance for these pathogens.

show abstract

“…Across Mexico, rickettsiae pathogens have been described in vectors and hosts in Northern Baja California, Sonora, Chihuahua [20], Campeche [21,22], Yucatan [23], Tabasco [24], Veracruz [22,25], Tamaulipas [25][26][27], and Coahuila [4,12,28]. Ongoing outbreaks of RMSF since 2008, with high fatality rates, in Northwestern regions of Mexico have been much of the focused surveillance, with human disease also reported from adjacent indigenous communities of Arizona [29][30][31][32][33].…”

Section: Introductionmentioning

confidence: 99%

Brown Dog Tick (Rhipicephalus sanguineus sensu lato) Infection with Endosymbiont and Human Pathogenic Rickettsia spp., Northern Mexico

Salomon¹,

Santos²,

Zecca³

et al. 2022

Preprint

View full text Add to dashboard Cite

Of the documented tick-borne diseases infecting humans in Mexico, Rocky Mountain spotted fever (RMSF), caused by the gram-negative bacterium Rickettsia rickettsia, is responsible for most fatalities. Given recent evidence of brown dog tick, Rhipicephalus sanguineus sensu lato, as an emerging vector of human RMSF, we aimed to evaluate dogs and their ticks for rickettsiae infections as an initial step in assessing the establishment of this pathosystem in a poorly studied region of northeastern Mexico while evaluating the use of dogs as sentinels for transmission/human disease risk. We sampled owned dogs living in six disadvantaged neighborhoods of Reynosa, Northern Mexico to collect whole blood and ticks. Of 168 dogs assessed, tick infestation prevalence was 53%, comprised of exclusively R. sanguineus s. l. (n=2,170 ticks). Using PCR and sequencing, we identified an overall rickettsiae infection prevalence of 4.1% (n=12/292) in ticks, in which eight dogs harbored at least one infected tick. Rickettsiae infections included R. amblyommatis and R. parkeri, both of which are emerging human pathogens, as well as candidatus R. andeanae. This is the first documentation of pathogenic Rickettsia in R. sanguineus s.l. collected on dogs from northeastern Mexico. Domestic dog infestation with Rickettsia-infected ticks indicates ongoing transmission, thus humans are at risk for exposure and underscores the importance of public and veterinary health surveillance for these pathogens.

show abstract

Rickettsiosis Caused by Rickettsia parkeri, Mexico

Cited by 10 publications

References 9 publications

An unusual identification ofRickettsia parkeriin synanthropic rodents and domiciliated dogs of a rural community from Yucatán, Mexico

An unusual identification ofRickettsia parkeriin synanthropic rodents and domiciliated dogs of a rural community from Yucatán, Mexico

Brown Dog Tick (Rhipicephalus sanguineus Sensu Lato) Infection with Endosymbiont and Human Pathogenic Rickettsia spp., in Northeastern México

Brown Dog Tick (<em>Rhipicephalus sanguineus</em> sensu lato) Infection with Endosymbiont and Human Pathogenic <em>Rickettsia</em> spp., Northern Mexico

Contact Info

Product

Resources

About