RIFM fragrance ingredient safety assessment, α-Irone, CAS registry number 79-69-6

Api, A.M.; Belsito, D.; Bhatia, S.P.; Bruze, M.; Calow, Peter; Dagli, M.L.; Dekant, W.; Fryer, A.D.; Kromidas, L.; Sullivan, G.; Lalko, J.; Lapczynski, A.; Liebler, Daniel C.; Politano, V. T.; Ritacco, G.; Salvito, D.; Shen, Jie; Schultz, T.W.; Sipes, I. G.; Wall, B.; Wilcox, D. K.

doi:10.1016/j.fct.2015.03.019

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion3

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Testing α-irone would have been of interest, but this molecule is unfortunately not a marketed allergen. 2,3 According to the Research Institute for Fragrance Materials (RIFM), the skin level of α-irone in formulas for use in cosmetics should not exceed 0.22%. 2,3 Based on a maximization test carried out in 25 patients, they observed no reaction to patch tests with α-irone 10% pet.…”

Section: Discussionmentioning

confidence: 99%

“…α‐Irone, or 6‐methyl‐β‐ionone, is used as a fragrance ingredient in cosmetics as well as in household cleaners and detergents. Testing α‐irone would have been of interest, but this molecule is unfortunately not a marketed allergen 2,3 …”

Section: Discussionmentioning

confidence: 99%

“…2,3 According to the Research Institute for Fragrance Materials (RIFM), the skin level of α-irone in formulas for use in cosmetics should not exceed 0.22%. 2,3 Based on a maximization test carried out in 25 patients, they observed no reaction to patch tests with α-irone 10% pet. However, they mentioned a study based on 1606 consecutive patients who were patch tested with a series of fragrance materials including α-irone 10% pet.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations