Background: Right atrial appendage rupture from blunt trauma is very uncommon, but is associated with a high mortality rate. Moreover, due to the paucity in available literature, our knowledge of the condition is still limited. Purposes: To emphasize a high degree of clinical suspicion in a case of cardiac tamponade after blunt chest trauma, quick diagnostic confirmation and urgent optimal management of such cases to save the patient and to avoid unnecessary and unacceptable delays. Case presentation: The author reports a 22-year-old female involved in a blunt chest trauma who was initially misdiagnosed and delayed management in a regional hospital, then transferred to our institution in a status of severe hypovolemic shock and cardiac tamponade with unconsciousness, intubation and mildly dilated and weakly reactive eyes/pupils. Fortunately, the patient was saved with quick diagnostic confirmation, urgent sternotomy and surgical repair of atrial appendage laceration for hemostasis associated with intra-and post-operatively intensive resuscitations. Conclusion: The important key to right atrial rupture diagnosis is a high degree of clinical suspicion in a case of cardiac tamponade following blunt chest trauma, especially with a hemodynamically unstable or compromised status. Aggressive resuscitation, prompt diagnosis, and urgent operation to repair the cardiac lesions are cornerstones to achieving an optimal outcome.