Purpose To use the two-dimensional speckle tracking technique (2D-STE) for the evaluation of right ventricular function in patients with triple vessels disease (TVD) without myocardial infarction.
Methods Thirty cases were randomly selected from health check-ups into group A. According to the results of their coronary arteriography (CAG), 60 individuals were chosen and split into two groups. TAPSE was determined using M-mode echocardiography; what measured the right ventricular diastolic transverse diameter (RVTD), the maximum peak velocity of the early and the late diastolic filling peak (E, A), end-systolic and end-diastolic area (RVESA, RVEDA) was conventional 2D echocardiography; E/A ratio and FAC were both calculated by the formula; Tissue Doppler was used to measure peak systolic peak early and late diastolic velocities (s', e', a') of the tricuspid annulus. end-systolic and end-dilation volume (RVESV, RVEDV) were measured by RT-3DE; 2D-STE was used to measure the global peak systolic strain (GS), peak early and late diastolic strain rate (SRe, SRa), as well as peak systolic strain rate (SRs). Correlations between GS and NT-pro BNP in subjects were assessed using Pearson linear correlation.
Results Compared with group A, e', e'/a' were reduced in group B (P<0.05), while s', E/A, RVEF, LVEF, FAC and TAPSE have no significantly difference (all P>0.05). RVEF, LVEF, E/A, e'/a', s', FAC and TAPSE were reduced, and RVESA, RVEDA, RVEDV, RVESV, and RVTD were increased in group C than in group A and B (all P<0.05). 2D-STE parameters: GS, SRe, SRa, SRs were reduced in groups B and C compared with group A (all P<0.05); correlation analysis showed that the correlation between GS and serum NT-pro BNP in groups B and C showed a negative correlation.
Conclusion 2D-STE can effectively recognize the early functional changes in the right ventricle in patients with triple vessels disease in coronary artery disease without myocardial infarction.