Right Ventricular Function with Standard and Speckle-Tracking Echocardiography and Clinical Events in Adults with D-Transposition of the Great Arteries Post Atrial Switch

Καλογερόπουλος, Ανδρέας; Deka, Anjan; Border, William L.; Pernetz, Maria A.; Georgiopoulou, Vasiliki V.; Kiani, Jawad; McConnell, Mike; Lerakis, Stamatios; Butler, Javed; Martin, Randolph P.; Book, Wendy

doi:10.1016/j.echo.2011.12.003

Cited by 67 publications

(47 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nonetheless, global longitudinal strain has been shown to have prognostic utility in assessing the systemic RV in D-TGA after atrial switch and the LV in repaired TOF. 308,309 Echocardiography With Contrast Poor image quality may require the use of alternate strategies to complete a patient's echocardiographic assessment. Ultrasound contrast agents used with harmonic imaging are indicated to opacify the LV chamber and enhance endocardial borders of the LV.…”

Section: Strain Imagingmentioning

confidence: 99%

Congenital Heart Disease in the Older Adult

Bhatt¹,

Foster²,

Kuehl³

et al. 2015

Circulation

205

View full text Add to dashboard Cite

Section: Strain Imagingmentioning

confidence: 99%

Congenital Heart Disease in the Older Adult

Bhatt¹,

Foster²,

Kuehl³

et al. 2015

Circulation

205

View full text Add to dashboard Cite

“…5 RV strain analysis, on the other hand, has only been performed in a few studies using 6 segments (6S) from one view (apical 4-chamber). 6–8 To our knowledge, there are no studies using an 18S three-view RV strain analysis model. Early work during the development of this approach to RV strain analysis was performed in a systemic RV population (D-transposition of the great arteries post atrial switch) in our institution, and suggested the potential need for comprehensive image acquisition due to important findings seen outside of the 4-chamber RV apical view (unpublished data).…”

Section: Introductionmentioning

confidence: 99%

Right Ventricular Mechanics Using a Novel Comprehensive Three-View Echocardiographic Strain Analysis in a Normal Population

Forsha

Risum

Kropf

et al. 2014

Journal of the American Society of Echocardiography

View full text Add to dashboard Cite

Background While quantitative RV strain analysis may be useful in congenital and acquired heart disease populations with RV failure, a comprehensive, standardized approach is lacking. An 18 segment RV strain analysis obtained from 3 standardized RV apical echo images was used to determine the feasibility, normal values and reproducibility of the method in normal adults. Methods Forty healthy, prospectively-enrolled volunteers with no cardiac history and normal QRS duration received an echo optimized for strain analysis including 3 RV apical views. 2D speckle tracking longitudinal strain analysis was performed on EchoPAC software. Eleven retrospectively-identified subjects with RV disease were included as a pilot population. All had been imaged using the same protocol including the 3 RV apical views. Results All control subjects had normal anatomic morphology and function by echo. Feasibility of the RV strain analysis was good (adequate tracking in 696/720 (97%) of segments). RV global peak systolic strain was −23 ± 2%. Peak strain was highest in the RV free wall and lowest in the septum. Dyssynchrony indices demonstrated no dyssynchrony using LV criteria. Reproducibility of most strain measures was acceptable. This methodology identified important disease not seen in the 4-chamber apical view alone in the pilot population of 11 patients with RV disease. Strain pattern and values were different from the control population indicating differences do exist from normal. Conclusions The 18 segment RV strain analysis is feasible with strain measures falling into discrete ranges in this normal population. Those with RV disease illustrate the potential utility of this approach. These data indicate that this model can be utilized for more detailed studies evaluating abnormal RV populations where its full potential can be assessed.

show abstract

“…This finding is of clinical importance, considering the papers by Kalogeropoulos et al [16] and Diller et al [17], which reported that reduced global longitudinal strain is associated with a higher risk of adverse clinical events (progression to NYHA class ≥ 3, clinically relevant cardiac arrhythmia, or death) in patients with subaortic RV. In the present study, BMI correlated weakly with the global longitudinal strain values.…”

Section: Discussionmentioning

confidence: 91%

Assessment of systemic right ventricular function in adult overweight and obese patients with congenitally corrected transposition of the great arteries

Kowalik¹,

Klisiewicz²,

Biernacka³

et al. 2017

Kardiol Pol

View full text Add to dashboard Cite

A b s t r a c t Background:In congenitally corrected transposition of the great arteries the right ventricle (RV) supports systemic circulation, and patients are prone to develop heart failure over time. Chronic volume overload secondary to obesity may contribute to premature dysfunction of the systemic RV. Aim:The aim of our study was to assess the systemic RV function in overweight/obese adult patients with congenitally corrected transposition of the great arteries. Methods:Transthoracic echocardiographic studies and laboratory testing (N-terminal pro-B-type natriuretic peptide [NT-proBNP] assessment) were performed in patients with congenitally corrected transposition, who were scheduled for a routine examination, and the body mass index was calculated for each patient. Results:We studied 56 adults (31 men; mean age 33.9 years); 22 of whom were overweight (body mass index [BMI] of 25-29.9 kg/m 2 ) or obese (BMI of 30 kg/m 2 or more), and 34 of whom were normal weight (BMI below 25 kg/m 2 ). Age, gender, heart rate, and blood pressure were similar in both groups. The mean NT-proBNP levels were not significantly different. On echocardiography, the overweight/obese patients had a decreased systemic RV fractional area change (0.38) compared to normal weight patients (0.43); p = 0.02. Moreover, a significant reduction in the global longitudinal strain in the overweight/obese group was observed (-15.3% vs. -18.3%; p = 0.01).Conclusions: Overweight/obesity in adult patients with congenitally corrected transposition of the great arteries is associated with impaired systemic RV function.

show abstract

Right Ventricular Function with Standard and Speckle-Tracking Echocardiography and Clinical Events in Adults with D-Transposition of the Great Arteries Post Atrial Switch

Cited by 67 publications

References 57 publications

Congenital Heart Disease in the Older Adult

Congenital Heart Disease in the Older Adult

Right Ventricular Mechanics Using a Novel Comprehensive Three-View Echocardiographic Strain Analysis in a Normal Population

Assessment of systemic right ventricular function in adult overweight and obese patients with congenitally corrected transposition of the great arteries

Contact Info

Product

Resources

About