Background:This study aims to present the outcomes of primary single-stage arterial switch and ventricular septal defect closure operation in patients with Taussig-Bing anomaly. Methods: Between November 2004 and November 2015, a total of 41 patients (33 males, 8 females; median age 38 days; range 4 to 1,239 days) who underwent primary arterial switch procedure with the diagnosis of Taussig-Bing anomaly were retrospectively analyzed using the hospital database. Demographic data, echocardiograms, cardiac catheterization reports and operative notes were reviewed. Results: In-hospital mortality occurred in six patients (14.3%). Risk factors associated with in-hospital mortality were cardiopulmonary bypass time (p=0.047; Exp (B)=1.0222) and aortic arch obstruction (p=0.023; RR=NA). The mean follow-up was 3.5 (range 0.1-10.9) years. A total of 27 (77%) of 35 survivors were followed. Late mortality was seen in three patients (11.1%). Freedom from reoperation was 96% at one year and 84% at five and 10 years. The only factor associated with late mortality was the coronary pattern 1LAD-2R, Cx (p=0.025; RR=16; %95 CI= 2-128). Conclusion:Primary arterial switch operation is safe and effective in the repair of Taussig-Bing anomaly. Despite an increased risk in patients with aortic arch obstruction, single-stage approach seems to be preferable.