Right ventricular wall thickness indexed to body surface area as an echocardiographic predictor of acute pulmonary embolism in high-risk patients

Wiliński, Jerzy; Skwarek, Anna; Borek, Radosław; Chukwu, Ositadima; Ciuk, Katarzyna; Stolarz‐Skrzypek, Katarzyna; Rajzer, Marek

doi:10.33963/kp.a2021.0180

Cited by 6 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the review by Pruszczyk and Konstantinides, elevated echocardiography imaging indexes are included in risk factors that may affect initially normotensive patients with PE and move them to the group of patients with intermediate-risk [35]. Another study aimed to assess usefulness of classic echocardiographic parameters indexed to height and body surface area for prediction of acute PE in patients with a high clinical probability of PE referred for computed tomography pulmonary angiography [36]. The authors of an expert opinion screening for patients with chronic thromboembolic pulmonary hypertension after acute PE claim that TTE is a preferred screening test for chronic thromboembolic pulmonary hypertension and should be performed in any patient with dyspnea of unclear cause after a history of acute PE and at least 3 months of optimal antithrombotic therapy [37].…”

Section: Discussionmentioning

confidence: 99%

Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK): A novel independent predictor of 30-day mortality in patients with acute pulmonary embolism

Wiliński¹,

Skwarek²,

Borek³

et al. 2022

Kardiol Pol

View full text Add to dashboard Cite

Background:The most commonly used parameter of right ventricular (RV) systolic function -tricuspid annular plane systolic excursion (TAPSE) -is unavailable for some patients. Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK) has been proposed as its alternative. Aim:The study aimed to assess the feasibility of SEATAK use in patients with acute pulmonary embolism (PE) and its value in prognosis after PE. Methods:The observational study included 164 consecutive patients (45.7% men; average age, 70 years) with a high clinical probability of PE referred for computed tomography pulmonary angiography.Results: SEATAK was unavailable due to inadequate quality of echocardiogram in 2.8% of patients, whereas TAPSE could not be calculated in 4.9%, both parameters were not estimated only in 0.6%. SEATAK and TAPSE values did not differ between groups of patients with PE (n = 82) and without (n = 82). In the whole study, SEATAK correlated positively with TAPSE (r = 0.71; 95% confidence interval [CI], 0.62-0.78; P <0.001), fractional area change of the RV, left ventricular ejection fraction, and peak systolic tricuspid annular velocity assessed with tissue Doppler imaging. There were only 3 echocardiographic predictors of 30-day all-cause mortality in patients with with PE (n = 10): SEATAK, pulmonary acceleration time, and the 60/60 sign. SEATAK predicted 30-day all-cause mortality with AUC (area under the curve) 0.726 (95% CI, 0.594-0.858; P = 0.01) and 30-day PE-related mortality (n = 4) with AUC, 0.772 (95% CI, 0.506-0.998; P = 0.03).Conclusions: SEATAK is a promising practicable echocardiographic parameter reflecting RV systolic function and might be an accurate alternative to TAPSE. Moreover, SEATAK could be an independent predictor of all-cause and PE-related 30-day mortality in patients with acute PE.

show abstract

Section: Discussionmentioning

confidence: 99%

Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK): A novel independent predictor of 30-day mortality in patients with acute pulmonary embolism

Wiliński¹,

Skwarek²,

Borek³

et al. 2022

Kardiol Pol

View full text Add to dashboard Cite

show abstract

“…A standard diagnostic protocol comprised determination in all patients on the day of admission to the ward the laboratory parameters including serum concentrations of troponin T, N-terminal pro B-type natriuretic peptide (NT-proBNP) and D-dimer with laboratory methods summarized formerly [14]. TTE was performed within 24 hours after admission to the ward by an experienced sonographer cardiologist (JW) using echocardiographic systems of Vivid S60N or Vivid S6 (General Electric Company, Boston, MA, US) according to the unified protocol [14][15][16]. The measurements were made based on the current guidelines of European Association of Cardiovascular Imaging with real-time electrocardiographic recording executed in order to accurately define the heart cycle phases [17].…”

Section: Methodsmentioning

confidence: 99%

Echocardiographic parameters as adjuncts to the Pulmonary Embolism Severity Index in predicting 30-day mortality in acute pulmonary embolism patients

Wiliński,

Chukwu,

Skwarek

et al. 2024

Pol Heart J

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

“…Commercially available echocardiographic systems of Vivid S60 N or Vivid S6 (General Electric Company, Boston, Massachusetts, United States of America) were used. All TTEs were executed according to a predefined protocol [16,17]. The measurements were made based on the current guidelines of the European Association of Cardiovascular Imaging (EACVI) with real-time electrocardiographic recording in order to precisely define the phases of the heart cycle [18].…”

Section: Methodsmentioning

confidence: 99%

Indexing of Speckle Tracking Longitudinal Strain of Right Ventricle to Body Surface Area Does Not Improve Its Efficiency in Diagnosis and Mortality Risk Stratification in Patients with Acute Pulmonary Embolism

Wiliński,

Skwarek,

Borek

et al. 2023

Healthcare

Self Cite

View full text Add to dashboard Cite

Background: Acute pulmonary embolism (PE) is associated with a serious mortality rate. Thus, the rapid diagnosis and identification of patients at high risk of death is pivotal. The search for echocardiographic parameters for this purpose continues. Recent publications reveal correlations between myocardial longitudinal strain (LS) and body surface area (BSA). The aim of the study was to evaluate the usefulness of indexing the right ventricular (RV) speckle tracking LS to BSA in detecting PE and stratifying the risk of 30-day all-cause mortality. Methods: the prospective cross-sectional observational study group consisted of 167 consecutive patients (76 men, 45.5%) aged 69.5 ± 15.3 years, and they were referred for computed tomography pulmonary angiography. Patients underwent a transthoracic echocardiographic examination within 24 h of admission to the hospital ward. RVLS and their derivatives indexed to BSA were included in the analysis. Results: PE was confirmed in 88 patients, while 79 patients had no radiological features of PE. The only echocardiographic parameters that differed between subgroups were pulmonary flow acceleration (Act), McConnell’s sign, LS of the middle segment of the RV free wall, and its derivative indexed to BSA. During the 30-day follow-up of a subgroup of subjects with PE, 12 patients died. The mortality predictors with increasing prediction value included a RV free wall mid-segment LS (cut-off value: −21%, Area Under the Curve—AUC 0.6, p = 0.02) and its derivative indexed to BSA (−14 %/m2, AUC 0.62, p = 0.003), body mass index (24.7 kg/m2, AUC 0.63, p = 0.002), D-dimer serum concentration (3559 pg/mL, AUC 0.66, p < 0.001), Act (67 ms, AUC 0.67, p < 0.001), septal basal LS (−15%, AUC 0.68, p = 0.02), RV free wall basal segment LS (−14%, AUC 0.7, p = 0.015), age (66 years, AUC 0.74, p = 0.004), NT-proBNP (1120 pg/mL, AUC 0.75, p = 0.01), troponin T (66 ng/mL, AUC 0.78, p = 0.005), and the complex score of the Pulmonary Embolism Severity Index (AUC 0.88, p < 0.001). Conclusions: indexing of RVLS to BSA does not improve its prognostic value in patients with acute PE.

show abstract

Right ventricular wall thickness indexed to body surface area as an echocardiographic predictor of acute pulmonary embolism in high-risk patients

Cited by 6 publications

References 9 publications

Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK): A novel independent predictor of 30-day mortality in patients with acute pulmonary embolism

Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK): A novel independent predictor of 30-day mortality in patients with acute pulmonary embolism

Echocardiographic parameters as adjuncts to the Pulmonary Embolism Severity Index in predicting 30-day mortality in acute pulmonary embolism patients

Indexing of Speckle Tracking Longitudinal Strain of Right Ventricle to Body Surface Area Does Not Improve Its Efficiency in Diagnosis and Mortality Risk Stratification in Patients with Acute Pulmonary Embolism

Contact Info

Product

Resources

About