In August 2014, in situ measurements revealed an intense salinity drop impacting South Florida coral reefs, between Pulley Ridge (Southwest Florida Shelf) and the Florida Keys. The low salinity waters had a surface signal of 32 (down from 35.2) and extended over a 15-20-m deep lens. Satellite observations showed that this abrupt drop in salinity was due to a southeastward export of Mississippi River waters from the Northern Gulf of Mexico (GoM), revealing strong interaction between coastal and oceanic flows. Unlike previous events of marked long-distance Mississippi water export, this episode is not associated with Mississippi flooding conditions, which makes it a unique study case. We have developed a highresolution (~2 km) comprehensive hydrodynamic numerical model of the GoM to study the conditions that controlled the 2014 Mississippi River water export episode. It is based on the Hybrid Coordinate Ocean Model (HYCOM) and assimilates remotely sensed altimetry and sea surface temperature observations, to ensure that the simulated upper-ocean is realistic.