Rilonacept in the treatment of subacromial bursitis: A randomized, non-inferiority, unblinded study versus triamcinolone acetonide

Abstract

While improvement in QuickDASH and pain was noted with a single intrabursal injection of rilonacept at 4 weeks, injection with triamcinolone acetonide was more efficacious. This trial was registered with www.clinicaltrials.gov (NCT01830699).

Comparison of Early Results Between Single and Quadruple Injection of Corticosteroid-local Anesthetic in Patients with Subacromial Impingement

“…The optimal dosage, concentration and volume in the subacromial space are still controversial (9). There are several studies on the combinations of corticosteroid suspension with either high-volume (23,24) or lowvolume (25). A study involving two groups of 26 patients reported that 3 cc lidocaine + 1 cc triamcinolone and 9 cc lidocaine + 1 cc triamcinolone yielded comparable results during a follow-up of 8 weeks (9).…”

Shoulder and Neck Pain: Interdisciplinary Aspects of Treatment

“…В обеих группах было достигнуто статистически значимое уменьшение боли через 4 нед., более выраженное в группе триамцинолона (p = 0,044). С учетом высокой частоты эпизодов диареи и головной боли триамцинолон продемонстрировал некоторые пре-имущества по сравнению с рилонацептом для лечения больных с субакромиальным бурситом [47].…”

Efficacy of high-volume vs very low volume corticosteroid subacromial injection in subacromial impingement syndrome: a randomized controlled trial

“…Generally, when compared to low-volume CI, HVCI of lidocaine is associated with a higher risk of consequences, in particular, soft tissue irritation. And furthermore, when corticosteroids are at lower concentrations, the steroid effects decrease, which should only be acceptable if being using for therapeutic purposed 8 . In the case of patient, the pain and functional outcomes of the corticosteroid injection were satisfactory.…”