In nineteenth-century Britain, the role of the state in the cultivation of scientific activity was controversial. After the conclusion of the Napoleonic Wars in 1815, successive governments rolled back the apparatus of the ‘fiscal-military state’, characterized by high taxation and government spending. What followed was a moment of self-avowedly laissez-faire, liberal governance in which contemporaries placed great emphasis on the value of minimal government intervention in market activity. This not only concerned the nation’s social and economic life, but its scientific culture. Leading political and scientific figures frequently promoted science as something best advanced if left to individuals. Yet by the 1900s, the British state was increasingly engaged in financing and organizing large-scale scientific research. The twentieth century would see governments around the world expand their scientific and technological investment, epitomized by the American concept of ‘Big Science’. This article analyses the relationship between the British government and scientific activity during the nineteenth century and argues that, far from a simple matter of minimal intervention, the state was always highly active in the market of science.