Because COVID-19 occurred in 2019, the behavioxr of humans has been changed and it will influence the business model of enterprise. Enterprise cannot predict its development according to past knowledge and experiment; so, it needs a new machine learning framework to predict enterprise performance. The goal of this research is to modify AdaBoost to reasonably predict the enterprise performance. In order to justify the usefulness of the proposed model, enterprise data will be collected and the proposed model can be used to predict the enterprise performance after COVID-19. The test data correct rate of the proposed model will be compared with some of the traditional machine learning models. Compared with the traditional AdaBoost, back propagation neural network (BPNN), regression classifier, support vector machine (SVM) and support vector regression (SVR), the proposed method possesses the better classification ability (average correct rate of the proposed method is 88.04%) in handling two classification problems. Compared with traditional AdaBoost, one-against-all SVM, one-against-one SVM, one-against-all SVR and one-against-one SVR, the classification ability of the proposed method is also relatively better for coping with the multi-class classification problem. Finally, some conclusions and future research will be discussed at the end.