Risk Assessment of Death of Tumor-Related PTE by CAR Combined with DD Detection

Li, Xinran; Zheng, Jie; Lu, Yu‐Chuan; Pan, Xiaowen

doi:10.2147/vhrm.s365323

Cited by 2 publications

(1 citation statement)

References 21 publications

(19 reference statements)

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“…Both of these suggest that there are localized diffuse hemorrhage and fibrin thrombus in the myometrium of patients with adenomyosis We hypothesize that the exposure of endometrial vasculature due to curettage, the entry of fibrin thrombi and related coagulation factors such as tissue factor and fibrinogen into the circulation from microhemorrhagic foci, and surgical emergency (significantly elevation of CRP), contributed to abnormal coagulation function and hypercoagulable state of the body, further causing thrombosis or PE. Our previous studies found significantly increased CRP, decreased AT, and increased FIB levels in many patients with PE, [ 17 , 18 ] which was consistent with the situation in this patient.…”

Section: Discussionsupporting

confidence: 91%

Pulmonary embolism after diagnostic curettage in patient with adenomyosis and hysteromyoma: A case report and brief review of literature

Cheng,

Yan,

et al. 2023

Medicine

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Rationale: Pulmonary embolism (PE) is a common cause of cardiovascular death whose major acquired risk factors include postoperative states, pregnancy, malignancy, and age. We report a case of PE that occurred after diagnostic curettage for abnormal uterine bleeding, with a medical history of adenomyosis and hysteromyoma. Patient concerns and diagnoses: A 31-year-old Han Chinese female was referred to our hospital with menstrual disorders, increased menstrual flow, and severe anemia. After admission, the patient was treated with a blood transfusion, iron supplementation, and erythropoietin, and diagnostic curettage was performed the following day. On the first postoperative day, the patient developed pulmonary embolism with dyspnea and fever diagnosed by CT pulmonary angiography and significantly elevated D-dimer. Interventions and outcomes: Molecular weight heparin was administered for PE for 2 weeks, dyspnea was relieved significantly after 2 days of treatment and the uterine bleeding did not increase; and gonadotropin-releasing hormone agonists were administered for adenomyosis after 1 week of anticoagulant therapy to reduce bleeding. We followed up for 6 months, and the patient had no recurrence of thrombosis and uterine bleeding had improved. Conclusion: We speculate that the occurrence of pulmonary embolism was closely related to adenomyosis, hysteromyoma, and curettage in this patient. Treating the presence of both menstrual bleeding and thromboembolism is challenging, and careful management is necessary to avoid therapeutic contradictions.

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Section: Discussionsupporting

confidence: 91%