Risk assessment via oral and dermal pathways from heavy metal polluted water of Kolleru lake - A Ramsar wetland in Andhra Pradesh, India

Sharma, Somya

doi:10.5620/eaht.2020019

Cited by 12 publications

(14 citation statements)

References 31 publications

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“…Ideally, THQ ≤ 1 implies that the exposure is unlikely to exert adverse health effects whereas THQ > 1 represent a possibility of non-carcinogenic effects [36]. In this assessment, the augmentative effect of toxicants (the cumulative risk or total THQ) was considered as the sum of the individual metal THQ values (Equation 4) [39]. The assumption made during the health risk calculations was that the ingested/adsorbed dose is equal to the dose absorbed into the body.…”

Section: Estimated Daily Intake and Target Hazard Quotientmentioning

confidence: 99%

Physicochemical Quality and Health Risks Associated with Use of Water from Nyamwamba River, Kasese, Western Uganda

Masereka

Byamugisha

Adaku

2022

AJACR

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Aim: In Kasese district of Western Uganda, farmers cultivating near Nyamwamba River (NR) experience crop wilting whenever the river banks burst. Increased cases of cancer and ulcers in the district is anecdotally blamed on ingestion of contaminated water from water resources polluted by tailings from Kilembe copper mines. Sand miners attested that mining in NR caused body irritations and itching while drinking water from the same river results in abdominal complications in infants. The aim of this study was to assess the seasonal variations in the physicochemical parameters and heavy metals (HMs) content of water from NR, and the associated health risks. Place and Duration of Study: The experiments were done at the Department of Chemistry, Faculty of Science, Mbarara University of Science and Technology, Uganda from 2018 to 2019. Methodology: This study employed quantitative research design. Water was sampled from down, middle and upstream of NR and Mubuku River, Western Uganda during the dry and wet seasons. The samples were analyzed for physicochemical parameters (pH, conductivity, total dissolved solids, total suspended soils) and HMs: chromium (Cr), cadmium (Cd), zinc (Zn), iron (Fe), lead (Pb), arsenic (As) and copper (Cu) by atomic absorption spectrometry. The estimated daily intake (EDI), target harzard quotient (THQ) and cancer risks were calculated to explore if there are any carcinogenic and non-carcinogenic health risks that could arise from ingestion and dermal contact with water from NR. Results: Most physicochemical parameters of the water samples only met WHO guidelines for drinking water in the upstream. The mean concentration of Fe, Cu, Pb, Zn, Cr, Cd and As were 0.90-29.66 mg/L, 0.21-10.74 mg/L, 0.40-8.21 mg/L, 1.10-13.47 mg/L, 0.79-13.47 mg/L, 0.05-1.40 mg/L and 0.22-4.34 mg/L, respectively. Wet season recorded higher HMs concentrations when compared to the dry season, with all its samples exceeding the WHO guidelines for drinking water. There was an extremely high concentration of HMs in the upstream samples than expected. Health risk assessment indicated that the EDI through dermal contact ranged from 0.015 to 4.150 mg/kg/day while through ingestion of contaminated water, the values ranged from 0.008 × 10-6 to 38.266 × 10-6 mg/Lday. Some of the EDI doses were higher than corresponding reference doses for ingestion and contact with the HMs in water. THQ and total THQ exceeded 1 while cancer risk values were beyond the US EPA cancer risk borderline. Conclusion: This study revealed that there are serious non-carcinogenic and carcinogenic health risks that could arise from consumption and contact with water from NR. Future studies should examine the relationship between the occurrence of trace metals in food stuffs with cancer, ulcers and other associated diseases in the area.

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Section: Estimated Daily Intake and Target Hazard Quotientmentioning

confidence: 99%

Physicochemical Quality and Health Risks Associated with Use of Water from Nyamwamba River, Kasese, Western Uganda

Masereka

Byamugisha

Adaku

2022

AJACR

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“…Hazard index (HI) is the cumulative potential for noncarcinogenic effects from more than one heavy metal through dermal or ingestion (C. zillii) pathways and can be Chronic from equation 5 (Sharma, 2020).…”

Section: Hazard Index (Hi)mentioning

confidence: 99%

Hazard Identification and Potential Risk Analysis of Toxic Metals in Redbelly Tilapia (Coptodon zillii) Consumed and Surface Water from the Niger Delta Estuary

Davies,

Amaewhule,

Nkeeh

2024

International Journal of Environment and Geoinformatics

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Anthropogenic activities have caused toxic metals to escalate, polluting rivers, and accumulating in water, sediments, and fish. This harms aquatic ecosystems and has enduring impacts on humans and aquatic life. The study aimed to assess the accumulation of heavy metals (Pb, Cr, Cu, Fe, Ni, Cd, and Zn) in Redbelly tilapia (Coptodon zillii) and water obtained from three sampling stations along Atuka Creek which is a crude oil-contaminated site in a southern creek in Nigeria. The investigation further intends to evaluate potential health risks linked to the consumption of C. zillii and to analyze the pollution and productivity levels of the corresponding aquatic ecosystem. The results show significant variations in heavy metal concentrations across stations, with Station 1 exhibiting the highest contamination levels attributed to its proximity to pollution sources. The fish from Station 1 revealed elevated levels of contamination, surpassing recommended limits for Pb, Fe, Ni, and Zn. Calculations of chronic daily intake (CDI) values indicate potential health risks for both adults and children, particularly in Stations 1 and 2. The hazard quotient (HQ) and hazard index (HI) values surpassed safe limits in these stations, suggesting non-carcinogenic health risks linked to fish consumption and swimming. Moreover, lifetime cancer risk (ILCR and TLCR) assessments revealed an augmented risk of cancer, especially in Stations 1 and 2. These findings emphasize the need for stern pollution control measures, regulations, and remediation strategies to mitigate heavy metal contamination, ensure water quality, and safeguard public health in southern Nigerian communities.

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“…Hazard index (HI) is the cumulative potential for noncarcinogenic effects from more than one heavy metal through ingestion pathways and can be estimated from equation 2 (30).…”

Section: Hazard Index (Hi)mentioning

confidence: 99%

Evaluation of Heavy Metal Pollution in Commonly Consumed Mollusc (Crassostrea gasar) from Elechi Creek, River State, Nigeria and the Health Risk Implications

Davies,

Anyanwu,

Amaewhule

2024

Journal of the Turkish Chemical Society Section A: Chemistry

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Marine biotas are used to assess potential adverse human health risks associated with consuming protein-rich aquatic organisms. Heavy metal content of Mangrove oysters (Crassostrea gasar) was evaluated between January and June 2022 in 3 stations. Six heavy metals (copper, cadmium, zinc, lead, arsenic and iron) were determined using standard methods. Target Hazard Quotient (THQ) and Hazard Index (HI) were used for the non-carcinogenic assessment while Target Cancer Risk (TR) was used for the carcinogenic assessment of the potential human health risk of consuming the oysters. The heavy metal values recorded were Cu (473.2 – 596.7 mg/kg), Cd (2.33 – 3.84 mg/kg), 209.02 – 246.41 mg/kg), Pb (6.16 – 12.07 mg/kg), As (0.012 – 0.016 mg/kg) and Fe (1609.0 – 1846.0 mg/kg). All the heavy metals were above the acceptable limits except arsenic. Stations 2 and 3 had relatively higher values; attributed to anthropogenic activities. The THQ and HI values were less than 1 in all the metals and stations while TR for Pb and arsenic were within the negligible range in all the stations. However, Cd was unacceptable among the children in station 2. Station 3 had relatively higher values while the children were more vulnerable to both non-carcinogenic and carcinogenic risks. In conclusion, the consumption of oysters from Elechi Creek is considered safe based on acceptable levels of the THQ, HI and TR; though Cd-TR for children (Station 2) was unacceptable.

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Risk assessment via oral and dermal pathways from heavy metal polluted water of Kolleru lake - A Ramsar wetland in Andhra Pradesh, India

Cited by 12 publications

References 31 publications

Physicochemical Quality and Health Risks Associated with Use of Water from Nyamwamba River, Kasese, Western Uganda

Physicochemical Quality and Health Risks Associated with Use of Water from Nyamwamba River, Kasese, Western Uganda

Hazard Identification and Potential Risk Analysis of Toxic Metals in Redbelly Tilapia (Coptodon zillii) Consumed and Surface Water from the Niger Delta Estuary

Evaluation of Heavy Metal Pollution in Commonly Consumed Mollusc (Crassostrea gasar) from Elechi Creek, River State, Nigeria and the Health Risk Implications

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