Risk characterization of antimicrobial resistance of Salmonella in meat products

Abstract

Antimicrobial resistance is considered to be a major public health concern in the framework of Horizon 2020. The risk to human health from foodborne antimicrobial resistant microorganisms can be determined and assessed using risk analysis tools in accordance with Codex principles. Therefore, the objective of this work was to determine the qualitative risk characterization of the presence of Salmonella resistant strains in meat products. Consequently, a total of 2050 whole and minced samples of poultry, pork and beef, were assessed. Samples were obtained by the Official Food Control Services of the Valencian administration (Spain), in the province of Valencia between January 2006 and June 2012. Salmonella was not found in any samples of beef. Salmonella strains isolated in poultry and pork samples were not resistant to amikacin, amoxicillin, cephalothin ciprofloxacin levofloxacin and ofloxacin. However, Salmonella isolates found in poultry had a high level of resistance to nalidixic acid, while those found in pork were more resistant to tetracycline and ampicillin. Furthermore, 41% of Salmonella isolates were resistant to three or more antibiotics. Finally, considering these results as exposure and taking into account the severity of the potential adverse health effects related to the different antimicrobials, risk characterization was estimated. As a result, three cases were classified as "Very high additional risk" all of them in minced meat, two cases in poultry (gentamicin and nalidixic acid) and one in pork (ampicillin). In the rest of the cases of resistance, the risk was classified as "high additional risk". This highlights the importance of continued surveillance and the need to take measures in the primary sector in order to minimize the risk for the consumer.2

Clonal Expansion of Biofilm-Forming Salmonella Typhimurium ST34 with Multidrug-Resistance Phenotype in the Southern Coastal Region of China

“…As previously reported, a major source of infection of S . Typhimurium in humans was the consumption of livestock products (Sallam et al, 2014 ; Doménech et al, 2015 ), which is consistent with our investigation here (Table 4 ). These findings may assist optimizing Hazard Analysis and Critical Control Point (HACCP) strategies in livestock abattoirs.…”

Prevalence, Serotyping, Molecular Typing, and Antimicrobial Resistance of Salmonella Isolated From Conventional and Organic Retail Ground Poultry

“…In a recent study, 36% of Salmonella isolates were multidrug resistant to two to five antimicrobials despite being isolated from a antimicrobials free turkey production facility ( Sanad et al, 2016 ). In a large study conducted in Spain, 41% of Salmonella isolates from meat products was resistant to three or more antibiotics ( Doménech et al, 2015 ). The high number of MDR Salmonella detected in retail meats sold in Oklahoma is not surprising since previous studies have shown the high incidence of MDR Campylobacter spp.…”

Current Challenges in Enhancing the Microbiological Safety of Raw Meat

“…Multidrug-resistant strains of commonly encountered pathogens, such as Salmonella, Campylobacter, Staphylococcus, and clostridia are well studied (Domenech et al, 2015;Zbrun et al, 2015;Doyle, 2015). Drug-resistant pathogens are of significance in both animal production and clinically, as a higher dose of antibiotics is required to treat conditions or alternative drugs need to be found to overcome resistance (Doyle, 2015;Seiffert et al, 2013;Woolhouse et al, 2015).…”