Risk evaluation of chemical contaminants in food in the context of RASFF notifications

Fürst, Peter; Milana, Maria Rosaria; Pfaff, Karla; Tlustos, Christina; Vleminckx, Christiane; Arcella, Davide; Barthélémy, Eric; Colombo, Paolo; Goumperis, Tilemachos; Pasinato, Luca; Torres, Ruth Roldán; Afonso, Ana M.

doi:10.2903/sp.efsa.2019.en-1625

Cited by 24 publications

(20 citation statements)

References 21 publications

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“…[ 7 ] The USA, China, and European Union stipulate that the highest permissible concentration of PAT in foodstuff is 50 µg kg −1 . [ 8 ] Regarding as its hazardous effect, the detoxification of PAT is necessary from food products to achieve more severe quality standards and safety necessities. Moreover, PAT has been noticed in different concentration in numerous industrial effluents, sewage effluents and other waste water ensuing in environmental hazards.…”

Section: Introductionmentioning

confidence: 99%

Green and Eco‐Friendly Removal of Mycotoxins with Organo‐Bentonites; Isothermal, Kinetic, and Thermodynamic Studies

Saeed

Farooq

Nafees

et al. 2020

CLEAN Soil Air Water

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In the current study the application of organo‐modified bentonite for the adsorption of mycotoxins (aflatoxin B1, citrinin, patulin, and zearalenone) is presented. The modification of clays is carried out using benzyl‐tri‐n‐butyl ammonium bromide (BTB), benzethonium chloride (BTC), and dioctyl sodium sulfosuccinate (DSS). Various experimental parameters such as pH, time, adsorbent dose, and mycotoxins concentration are thoroughly studied. The modified clays (B‐BTB, B‐BTC and B‐DSS) are characterized by X‐ray fluorescence, X‐ray diffraction, and Fourier transform infrared spectroscopy. The results depicted the high detoxification efficiency (≈99%) of modified clays for the removal of mycotoxins under optimized conditions (pH 5, time: 30 min, adsorbent amount: 50 mg). The adsorption capacities of modified clays are found in the order of: B‐BTC (AFB1: 18.02, CIT: 18.35, PAT: 18.21, ZEA: 18.09 mg g−1) > B‐BTB (AFB1: 17.7, CIT: 18.11, PAT: 17.95, ZEA: 17.90 mg g−1) > B‐DSS (AFB1: 17.5, CIT: 18.02, PAT: 17.86, ZEA: 17.80 mg g−1). The obtained results fitted well with thermodynamic, isothermal (Langmuir) and pseudo‐second order kinetics. Low cost organo‐modified bentonite shows the promise in mitigating mycotoxin contamination, which could improve food safety and reduce environmental contamination.

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Section: Introductionmentioning

confidence: 99%

Green and Eco‐Friendly Removal of Mycotoxins with Organo‐Bentonites; Isothermal, Kinetic, and Thermodynamic Studies

Saeed

Farooq

Nafees

et al. 2020

CLEAN Soil Air Water

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“…The output from RASNEX can be processed using the BfR FoodChain-Lab environment as well as be used as an input for other risk management applications. One example is the usage of the EFSA RACE tool [6] for retrospective risk evaluation using past RASFF notification analytical results (in an extension of the RACE use case intended by EFSA, prospective decision-making to report in RASFF). Laboratory analytical results can be extracted from RASFF using RASNEX and then be used as an input for the EFSA RACE tool.…”

Section: Advantages and Challenges Using Rasnexmentioning

confidence: 99%

“…RASFF is under the control of the European Commission and nationally in Germany under the following institutional contact: National RASFF-und AAC-Kontaktstelle outbreak from the European RASFF notifications and compile related information in sheets, thereby enabling the use of this data for further analysis with other tools (e.g. FoodChain-Lab [5], RACE [6] or other future tools). RASNEX generates a graphical mapping of all actors of the supply network known and extracted by the software and involved in contamination events.…”

Section: Introductionmentioning

confidence: 99%

“…Petroczi et al [11] who focused on summarizing mycotoxin transgressor and detector nations and extracting seasonal patterns. Likewise, efforts have been made to harmonize the decision process whether to launch a RASFF notification with the EFSA RACE-tool, albeit only for chemical contaminants [6]. The use of RASNEX is exemplified with the fipronil contamination incident of 2017/2018.…”

Section: Introductionmentioning

confidence: 99%

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Introducing the Rapid Alert Supply Network Extractor (RASNEX) tool to mine supply chain information from food and feed contamination notifications in Europe

et al. 2021

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Background During food or feed contamination events, it is of utmost importance to ensure their rapid resolution to minimize impact on human health, animal health and finances. The existing Rapid Alert System for Food and Feed (RASFF) is used by the European Commission, national competent authorities of member countries and the European Food Safety Authority to report information on any direct or indirect human health risk arising from food or feed, or serious risks to animal health or the environment in relation to feed. Nevertheless, no methods exist to to collectively evaluate this vast source of supply chain information. Methods To aid in the extraction, evaluation and visualization of the data in RASFF notifications, we present the Rapid Alert Supply Network Extractor (RASNEX) open-source tool available from https://doi.org/10.5281/zenodo.4322555 freely. Among RASNEX’s functions is the graphical mapping of food and feed supply chain operators implicated in contamination events. RASNEX can be used during ongoing events as a support tool for risk analysis using RASFF notifications as input. Results In a first use case, we showcase the functionality of RASNEX with the RASFF notification on a 2017/2018 contamination event in eggs caused by the illegal use of fipronil. The information in this RASFF notification is used to visualize nine different flows of main and related food products. In a second use case, we combine RASFF notifications from different types of food safety hazards (Salmonella spp., fipronil and others) to obtain wider coverage of the visualized egg supply network compared to the first use case. Actors in the egg supply chain were identified mainly for Italy, Poland and Benelux. Other countries (although involved in the egg supply chain) were underrepresented. Conclusions We hypothesize that biases may be caused by inconsistent RASFF reporting behaviors by its members. These inconsistencies may be counteracted by implementing standardized decision-making tools to harmonize decisions whether to launch a RASFF notification, in turn resulting in a more uniform future coverage across European food and feed supply chains with RASNEX.

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“…A 2-day sub-acute toxicity test of arsenic and 7-day sub-chronic toxicity test was carried out on adult catfish (8 months, 2 kg body weights). Five fishes were treated with arsenic 0.5-4 M in 15 L aquarium tank filled to 1/2 level with de-chlorinated water for the subacute toxicity test 15 . Five doses were prepared and used (0.1, 1, 2, and 4 M) using 2 fold dilution method alongside the control groups in this experiment.…”

Section: Evaluation Of Toxicity Effect Of Arsenicmentioning

confidence: 99%

Methanol Extract of Ficus platyphylla Stem Bark Inhibits Cholinesterase Enzyme on Catfish

2020

TJNPR

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treatment with the same extract resulted in no adverse effects in rat model. 8 Leaf extract from this plant was reported to exhibit high blood glucose-lowering effects, anti-nociceptive effect, ulcer healing effect, antioxidant effect, anti-inflammatory effect and anti-melanogenic effect. 9 However, to date, there is no available report on the anticholinesterase effect of the stem bark extract of this plant on the animal model. Therefore, the present study attempts to investigate the anticholinesterase effect of the stem bark extract of this plant on Catfish. Catfish also referred to as Pterygoplichthys is a large bony fish that is commonly found in Africa including Nigeria. 10 They are abundant in brackish water, freshwater, and saltwater and have been widely used in experimental research as the vertebrate animals for many years. 11 They are characterized by a moderate life cycle and life span with wide geographical range and availability. 12 The fish have been used as a suitable bio-indicator animal for the diagnosis of water pollutants caused by heavy metals due to their long-lived, reasonablly large size, and ability to adapt well to laboratory environment. 13 Moreover, this species is easy to be identified; they are known to have a fast growth rate and are easy to culture in the laboratory which make them an excellent research model. They are sensitive to toxicants and endocrine-disrupting chemicals at an early life stage. 14 Materials and Methods Plants collection and identification Ficus platyphylla stem bark was collected at Pharmacology garden city campus

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Risk evaluation of chemical contaminants in food in the context of RASFF notifications

Cited by 24 publications

References 21 publications

Green and Eco‐Friendly Removal of Mycotoxins with Organo‐Bentonites; Isothermal, Kinetic, and Thermodynamic Studies

Green and Eco‐Friendly Removal of Mycotoxins with Organo‐Bentonites; Isothermal, Kinetic, and Thermodynamic Studies

Introducing the Rapid Alert Supply Network Extractor (RASNEX) tool to mine supply chain information from food and feed contamination notifications in Europe

Methanol Extract of Ficus platyphylla Stem Bark Inhibits Cholinesterase Enzyme on Catfish

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