Risk factors affecting ICU admission in COVID‐19 patients; Could air temperature be an effective factor?

Abstract

Aim As the COVID‐19 pandemic has been spreading rapidly all over the world, there are plenty of ongoing works to shed on light to unknown factors related to disease. One of the factors questioned is also to be the factors affecting the disease course. In this study, our aim is to determine the factors that affect the course of the disease in the hospitalised patients because of COVID‐19 infection and to reveal whether the seasonal change has an effect on the disease course. Methods Our study was conducted on 1950 PCR test positive patients who were hospitalised for COVID‐19 disease between March 16 and July 15. Results As the seasonal temperature increases, decrease in WBC, PLT and albumin levels and increase in LDH and AST levels were observed. Risk of need for ICU has been found statistically significant (P < .05) with the increase in the age, LDH levels and CRP levels and with the decrease in the Ca and Albumin levels. Conclusions It is predicted with these results that, seasonal change might have affects on the clinical course of the disease, although it has no affect on the spread of the disease. And it might beneficial to check biochemical parameters such as LDH, CRP, Ca and Albumin to predict the course of the disease.

The effect of high-dose parenteral vitamin D3 on COVID-19-related inhospital mortality in critical COVID-19 patients during intensive care unit admission: an observational cohort study

“…The majority of critical patients in the ICU included in our study were male with the median age of 74 years. This finding was similar to the studies in the literature [24][25][26][27]. Among the comorbid diseases, only cardiovascular diseases were found to be significantly higher in the nonsurvivor group.…”

Red Blood Cell Distribution Width, Disease Severity, and Mortality in Hospitalized Patients with SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis

“…The overall SMD in RDW values between COVID-19 patients with mild vs. severe disease or survivor vs. non-survivor status in the 11 studies is shown in Figure 2. In 10 of these studies, patients with severe disease or non-survivor status displayed higher RDW values when compared to those with mild disease or survivor status (mean difference range, 0.13 to 2.01) [30][31][32][33][34][35][37][38][39][40]. However, the difference was not statistically significant in four studies [32,35,37,40].…”

“…After a full-text review of the remaining 12 articles, one further study was excluded because of missing information. Thus, 11 studies were included in the metaanalysis [30][31][32][33][34][35][36][37][38][39][40]. Their characteristics are presented in Table 1.…”

“…A total of 4901 COVID-19 patients were studied, 4247 (50% males, mean age 52 years) with low severity or who survived and 654 (57% males, mean age 66 years) with high severity or who died. Two studies were prospective [34,36], while the remaining nine were retrospective [30][31][32][33]35,[37][38][39][40]. Six studies were performed in Asia [30,33,35,[38][39][40], three in Europe [32,36,37], and two in America [31,34].…”

“…Two studies were prospective [34,36], while the remaining nine were retrospective [30][31][32][33]35,[37][38][39][40]. Six studies were performed in Asia [30,33,35,[38][39][40], three in Europe [32,36,37], and two in America [31,34]. End points included disease severity based on current clinical guidelines in six studies [30,[33][34][35]39,40], survival in three [31,36,37], and transfer to ICU in two [32,38].…”