Risk factors and mortality associated with Clostridium difficile-associated diarrhoea at a VA hospital

Changela, Ursula; Cannon, Joan P.; Aneziokoro, Chinyere; Shah, Palak; Thottapurathu, Lizy; Lentino, Joseph R.

doi:10.1016/j.ijantimicag.2004.07.011

Cited by 30 publications

(21 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Changela et al [25] studied veterans at the Hines VA (Chicago, IL) and found that levofloxacin use, the presence of comorbid conditions, and a higher mortality were associated with CDAD, but they did not examine spatial or seasonal trends, and the control group was not assayed for C. difficile, which may have allowed misclassification to occur. Similar to other studies, our data indicate that the use of antimicrobials (e.g., clindamycin and penicillin) is associated with increased risk of CDAD [4, 5, 22-24, 27, 28].…”

Section: Discussionmentioning

confidence: 99%

Fluoroquinolone Use and Risk Factors for Clostridium difficile-Associated Disease within a Veterans Administration Health Care System

McFarland

Clarridge

Beneda³

et al. 2007

Clinical Infectious Diseases

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Fluoroquinolone Use and Risk Factors for Clostridium difficile-Associated Disease within a Veterans Administration Health Care System

McFarland

Clarridge

Beneda³

et al. 2007

Clinical Infectious Diseases

View full text Add to dashboard Cite

“…A number of authors have sought to define patientlevel risk factors that predispose patients to CDAD. Most such analyses have examined patient demographics [7][8][9], comorbid conditions [10][11][12], clinical variables [7,8], and antibiotic treatment characteristics [7,8,13]. Patient-level risk factors have been used to help develop treatment algorithms [14], and may also be useful in developing prevention and control measures.…”

Section: Introductionmentioning

confidence: 99%

Predictors of Clostridium difficile colitis infections in hospitals

et al. 2007

View full text Add to dashboard Cite

Hospital-level predictors of high rates of 'Clostridium difficile-associated disease' (CDAD) were evaluated in over 2300 hospitals across California, Arizona, and Minnesota. American Hospital Association data were used to determine hospital characteristics associated with high rates of CDAD. Significant correlations were found between hospital rates of CDAD, common infections and other identified pathogens. Hospitals in urban areas had higher average rates of CDAD; yet, irrespective of geographic location, hospital rates of CDAD were associated with other infections. In addition, hospitals with 'high CDAD' rates had slower turnover of beds and were more likely to offer transplant services. These results reveal large differences in rates of CDAD across regions. Hospitals with high rates of CDAD have high rates of other common infections, suggesting a need for broad infection control policies. KeywordsArizona, California, clostridium difficile, cross infection, enterocolitis, pseudomembranous, geography, hospitals, humans, Minnesota, risk factors, urban population SUMMARYHospital-level predictors of high rates of ' Clostridium difficile-associated disease ' (CDAD) were evaluated in over 2300 hospitals across California, Arizona, and Minnesota. American Hospital Association data were used to determine hospital characteristics associated with high rates of CDAD. Significant correlations were found between hospital rates of CDAD, common infections and other identified pathogens. Hospitals in urban areas had higher average rates of CDAD ; yet, irrespective of geographic location, hospital rates of CDAD were associated with other infections. In addition, hospitals with 'high CDAD ' rates had slower turnover of beds and were more likely to offer transplant services. These results reveal large differences in rates of CDAD across regions. Hospitals with high rates of CDAD have high rates of other common infections, suggesting a need for broad infection control policies.

show abstract

“…can withstand and survive in situations in which there is a lack of nutrition. However, Bacillus cereus or Clostridium difficile, for example as spore formers in the health care facilities, must be completely sterilized to avoid nosocomial infectious diseases (Matsuki et al, 2005;Arrich et al, 2005;Changela et al, 2004;Hernaiz et al, 2004). Several colonies grew in MRSA selective culture medium, but only 1 colony was identified to be exactly MRSA and others were not MRSA.…”

Section: Methodsmentioning

confidence: 99%

Relationship between the Contamination of the Nurse's Caps and Their Period of Use in Terms of Microorganism Numbers

Shintani¹,

Hayashi

Sakakibara

et al. 2006

Biocontrol Sci.

View full text Add to dashboard Cite

Risk factors and mortality associated with Clostridium difficile-associated diarrhoea at a VA hospital

Cited by 30 publications

References 15 publications

Fluoroquinolone Use and Risk Factors for Clostridium difficile-Associated Disease within a Veterans Administration Health Care System

Fluoroquinolone Use and Risk Factors for Clostridium difficile-Associated Disease within a Veterans Administration Health Care System

Predictors of Clostridium difficile colitis infections in hospitals

Relationship between the Contamination of the Nurse's Caps and Their Period of Use in Terms of Microorganism Numbers

Contact Info

Product

Resources

About