Risk factors and poor prognostic factors of preeclampsia in Ibn Rochd University Hospital of Casablanca: about 401 preeclamptic cases

Abstract

Preeclampsia is a gestational pathology that complicates 2 to 8% of pregnancies and is one of the major causes of maternal and fetal morbidity and mortality worldwide. The aim of this work was to study the epidemiological profile of preeclampsia in Casablanca and to identify risk factors as well as factors of poor maternal and fetal prognosis. 401 preeclamptic cases were collected in the gynecology-obstetrics “C” Service of Lalla Meryem Maternity of Ibn Rochd University Hospital of Casablanca (2010-2011) were included in this study and a statistical analysis with the SPSS software version (16.0) was performed. We used the Chi-2 test to analyze qualitative variables and Student's test and ANOVA (analysis of variance) for quantitative variables. The incidence of preeclampsia was (7.1%). The epidemiological profile was that of a primipara (57.6%), average age 30 years and (66.8%) of pregnancies were not followed. Multiparity was a factor of poor maternal prognosis (p = 0.007). The low gestational age and no prenatal care were factors of maternal as well as fetal prognosis. Risk factors frequently found in our patients were obesity (15.21%) and chronic hypertension (5.73%) as vascular-renal history; abortion (16.46%) and perinatal death (5.24%) as obstetric history. Preeclampsia is a common obstetric pathology in our context. Better prenatal care and early diagnosis could reduce its incidence.

Management of pre-eclampsia and its complications in the department of gynecology and obstetrics at Donka national hospital Conakry, Guinea

“…During the study period we collected 217 cases of preeclampsia out of a total of 3054 deliveries, either a proportion of 7.10%. An identical proportion (7.1%) of pre-eclampsia was found in Morocco by Magee LA et al 5 Slightly higher proportions of pre-eclampsia were found in Togo (12.3%), Nigeria (10.2%), Pakistan (9.3%) and Mozambique (10.9%). 2,6…”

The Inter-Trimester Variation and Prognostic Value of Creatinine, Cystatin C and Uric Acid in Preeclamptic Patients: A Retrospective Study

“…Preeclampsia (PE) is the most common hypertensive disorder of pregnant women, with a morbidity of 3%-10% globally, causing significant maternal complications and fetal mortality [1]. In spite of this, the etiology of PE remains unclear; endothelial dysfunction and inflammation are thought to play a central role in its occurrence [2,3]. Kidney damage is one of the key components of the pathophysiological process involved in PE [4].…”

Changes in Serum Homocysteine Concentrations and their Prognostic Value in Pregnant Chinese Women with Preeclampsia : A Retrospective Study

“…Read Full License Background Preeclampsia (PE) is de ned as the onset of hypertension and proteinuria (> 300 mg/day) after 20 weeks of gestation, which changes the placental microenvironment and releases a series of maternal circulation factors, this serious pregnancy-speci c syndrome affects multiple organs, is detected in 5-8% of pregnancies worldwide, and there are no effective tools for the treatment of preeclampsia unless terminating pregnancy [1]. Although the pathogenesis of preeclampsia remains unclear, plausible theories include endothelial dysfunction, in ammation, and angiogenesis [2,3], there is emerging evidence that women with preeclampsia have higher homocysteine concentrations than healthy pregnant women [4].…”