2018
DOI: 10.1016/j.ajoms.2017.08.004
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Risk factors and treatments for medication-related osteonecrosis of the jaw: A 10-year single-institution experience

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Cited by 6 publications
(5 citation statements)
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“…With regard to elderly patients, the number of patients with cancer and osteoporosis has increased with the ageing population, and a concomitant increase in MRONJ patients has occurred. In our study, dental extraction or inflammatory dental disease was an important cause of MRONJ, similar to previous reports 1,9) .…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…With regard to elderly patients, the number of patients with cancer and osteoporosis has increased with the ageing population, and a concomitant increase in MRONJ patients has occurred. In our study, dental extraction or inflammatory dental disease was an important cause of MRONJ, similar to previous reports 1,9) .…”
Section: Discussionsupporting
confidence: 92%
“…Recent studies have indicated that surgical therapy is more effective than conservative therapy in MRONJ patients [7][8][9] . The mandible is more commonly disturbed by MRONJ than the maxilla [7][8][9] , and in cases of operation, preservation of inferior alveolar nerve (IAN) function is critical for maintaining quality of life 10) . Generally, the precise removal of bone in close vicinity to the IAN is difficult when using conventional instruments, such as rotary burs.…”
Section: Introductionmentioning
confidence: 99%
“…The organisms isolated from MRONJ are usually bacteria indigenous to the oral cavity, such as Actinomyces [7] . However, in this case, MRSA was detected in the fistula, probably due to the intermittent and prolonged use of antibacterial agents.…”
Section: Discussionmentioning
confidence: 99%
“…Infection is now thought key to MRONJ development [ 11 ], and bacteria are commonly found in biopsied necrotic tissue [ 40 , 41 ]. As MRONJ occurs in the mouth, and as the wound becomes exposed, the risk of bacterial infection is increased [ 13 , 42 ] while inflammation has been linked to MRONJ development, with it hypothesized that early, low level inflammation may be a trigger for the condition [ 43 ].…”
Section: Bisphosphonatesmentioning
confidence: 99%