Risk factors associated with hospitalization in patients with asymptomatic or mild COVID-19 in public accommodation facilities in Tokyo

Sakamoto, Yohei; Satoh, Kenichi; Tanaka, Takuma; Yamaguchi, Takayuki; Miyamoto, Tomomi; Sawaki, Kenji; Miyajima, Makiko; Nakaharai, Kazuhiko; Hoshina, Tokio; Horino, Tetsuya; Nakazawa, Yozo; Ikenoue, Tatsuyoshi; Yoshida, Masaki

doi:10.1016/j.jiac.2022.06.002

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…The high prevalence of disease progression and hospitalization in our cohort may have been caused by the alpha variant [18] and the higher age of our cohort population. Factors associated with hospitalization during isolation in our study were consistent with other reports, which again highlighted older age and higher BMI [16,17]. The clinical course of disease progression to ED visit or hospitalization in our cohort was similar to that reported in previous publications, which described progression to maximal symptom severity at 8-10 days after symptom onset [19].…”

Section: Discussionsupporting

confidence: 91%

“…The mortality rate of isolated patients with COVID-19 after triage was 0%. Concerning the hospitalization rate during isolation, the 10% observed in our cohort was high compared to recent studies in Japan (3.5-6.4%) [16,17]. The high prevalence of disease progression and hospitalization in our cohort may have been caused by the alpha variant [18] and the higher age of our cohort population.…”

Section: Discussioncontrasting

confidence: 55%

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Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

Tanaka

Yamamoto

Morimoto

et al. 2022

JCM

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Managing mild illness in COVID-19 and predicting progression to severe disease are concerning issues. Here, we investigated the outcomes of Japanese patients with mild COVID-19, and identified triage risk factors for further hospitalization and emergency department (ED) visits at a single tertiary hospital. A triage checklist with 30 factors was used. Patients recommended for isolation were followed up for 10 days for subsequent ED visits or hospital admission. Overall, 338 patients (median age, 44.0; 45% women) visited the clinic 5.0 days (median) after symptom onset. Thirty-six patients were immediately hospitalized following triage; others were isolated. In total, 72 non-hospitalized patients visited the ED during their isolation, and 30 were hospitalized after evaluation for oxygen desaturation. The median ED visit and hospitalization durations after symptom onset were 5.0 and 8.0 days, respectively. The checklist factors associated with hospitalization during isolation were age > 50 years, body mass index > 25 kg/m2, hypertension, tachycardia with pulse rate > 100/min or blood pressure > 135 mmHg at triage, and >3-day delay in hospital visit after symptom onset. No patients died. Altogether, 80% of patients with mild COVID-19 could be safely isolated at home. Age, BMI, underlying hypertension, date after symptom onset, tachycardia, and systolic blood pressure at triage might be related to later hospitalization.

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Section: Discussionsupporting

confidence: 91%

Section: Discussioncontrasting

confidence: 55%

Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

Tanaka

Yamamoto

Morimoto

et al. 2022

JCM

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“…Recently, Sakamoto et al has reported the clinical characteristics of COVID-19 patients who were admitted to public accommodation facilities and risk factors for hospitalization in metropolitan Tokyo [ 13 ]. In their research, 6.4% of patients were hospitalized, comparable to the present result (5.9%).…”

Section: Discussionmentioning

confidence: 99%

“…In fact, only 21% of patients had BMI ≥ 25 kg/m 2 in the present study. Sakamoto et al reported that age over 40 years and BMI ≥ 25 kg/m 2 were the risks for hospitalization in metropolitan Tokyo [ 13 ]. Importantly, the present study presented a novel risk score to identify the high-risk patients based on simple parameters including age, BMI, body temperature and SpO 2 .…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and the risk of hospitalization of patients with coronavirus disease 2019 quarantined in a designated hotel in Japan

et al. 2023

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The aim was to investigate the clinical characteristics of coronavirus disease 2019 (COVID-19) patients who were admitted to a designated hotel, and to clarify the risk factors for hospitalization of such patients with clinical deterioration. The medical records of COVID-19 patients who were admitted to the designated hotel in Mie Prefecture, Japan, between August 2020 and September 2021 were reviewed retrospectively. Of the 1,087 COVID-19 patients who were admitted to the designated hotel, 936 patients (32.1± 12.8 years, 61.3% male) were recruited after excluding patients under the age of 15 years (n = 33), those admitted from the hospital (n = 111, 10.2%), COVID-19 vaccinated patients (n = 4, 0.4%), and those who were discharged to their own home due to social disorders (n = 3). During the study period, 884 patients (94.4%) were discharged to their own home with improving symptoms, whereas 52 patients (5.6%) were hospitalized for a deteriorating clinical condition. The logistic regression analyses showed that older age (≥ 40 years), higher body mass index (≥ 25 kg/m2), hypertension were the risk factors for hospitalization. As the new risk scale score based on the results of the odds ratios increased, the hospitalization rate increased significantly: 2.0% at 0–1 points, 9.7% at 2–3 points, and 28.8% at 4–5 points (p < 0.001). None of the 52 hospitalized patients died, and none developed serious complications from COVID-19 after hospitalization. In conclusion, the designated accommodation program for COVID-19 patients was safe, especially for those with a low risk for hospitalization.

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Clinical Impact of Covid-19 Omicron Variant on Patients in Home Health Care

Ando,

Suzuki,

Yoshida

2024

Home Health Care Management & Practice

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Coronavirus disease 2019 (COVID-19) risk factors for hospitalization and mortality have been reported to be older age, comorbidities, and vaccination status. However, its clinical course and the risk of hospitalization and mortality in patients who received home health care for their predisposing status and diseases remain unclear. This study aimed to determine the characteristics and outcomes of these patients after being infected with the Omicron variant of COVID-19. This retrospective study included 33 patients diagnosed with COVID-19 after we initiated home health care. We classified the patients into 2 groups, that is, hospitalization (n = 7) and non-hospitalization (n = 26), and non-survival (n = 6) and survival (n = 27) and compared their backgrounds. COVID-19 severity was an affecting factor in hospitalization and survival. The nursing care environments and low daily life activities also affected hospitalization but not survival. The proportion of patients with terminal malignancies (50.0% vs 3.7%, p = .017) and the Charlson Comorbidity Index (5.0 vs 2.0, p = .096) were higher in the non-survival than in the survival group. Some patients had urinary tract infections and persistent weight and appetite loss (post COVID-19 syndrome), regardless of this improvement. Serum IL-6 levels were higher in patients with post COVID-19 syndrome than those without symptoms. Optimizing the nursing care environment is essential to continue home health care and lower the hospitalization rate even with SARS-CoV-2 infection. Post COVID-19 syndrome, such as appetite and weight loss, are associated with IL-6-induced inflammation.

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Risk factors associated with hospitalization in patients with asymptomatic or mild COVID-19 in public accommodation facilities in Tokyo

Cited by 3 publications

References 5 publications

Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

Clinical characteristics and the risk of hospitalization of patients with coronavirus disease 2019 quarantined in a designated hotel in Japan

Clinical Impact of Covid-19 Omicron Variant on Patients in Home Health Care

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