Risk factors associated with peripherally inserted central venous catheter-related large vein thrombosis in neurological intensive care patients

Abstract

Alterations in blood flow and consistency, but not vessel injury, appear associated with symptomatic thrombosis following placement of PICCs in neurological intensive care patients. Mannitol use and placement in a paretic arm are potentially modifiable risk factors. Given the high incidence rate of symptomatic thrombosis, future studies should focus on comparing cumulative complications of centrally inserted venous catheters and PICCs in intensive care patients.

Patterns, risk factors and treatment associated with PICC-DVT in hospitalized adults: A nested case–control study

“…For example, as has been previously reported, we found that patients with a history of VTE and those undergoing surgery with a PICC in place are more likely to develop thrombosis [7,15,21]. However, we add to this literature by reporting that both short and longer-duration surgical interventions appear to increase this risk, a finding previously not recognized in the literature.…”

Peripherally Inserted Central Catheters and Other Intravascular Devices: How Safe Are They for Hemodialysis Patients?

“…Symptomatic venous thrombosis occurs in fewer than 10% of patients with PICC lines 5-7 , but the overall rate of thrombosis, including both symptomatic and asymptomatic, reaches an astounding 38% 8 . The risk of venous thrombosis associated with PICC lines is two-fold higher in patients with chronic kidney disease (CKD) as compared to those with normal kidney function 9 .…”

Case Report

“…Lobo et al, 5 in a retrospective study of 777 patients, reported an incidence rate of 4.89%, while Evans et al 6 and King et al 7 reported incidence rates of 3% and 2%, respectively. Wilson et al, 8 in a retrospective study of 431 PICC placements, found the incidence rate of symptomatic thrombosis to be 8.4%. In a retrospective review of 2063 patients with PICC insertions, Chemaly et al 9 reported 52 PICC-associated VTEs, resulting in an incidence rate of 2.47%.…”