2022
DOI: 10.3390/idr14020026
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Risk Factors Associated with Poor Outcome in Patients with Infective Endocarditis: An Italian Single-Center Experience

Abstract: Background: Nowadays, infective endocarditis (IE) is still burdened by a high mortality. In the absence of an adequate prognostic stratification system, it is important to assess new predictors of poor outcomes. The aim of our study is to evaluate which factors were associated with higher mortality in IE patients. Methods: A retrospective cohort study enrolled patients with an IE diagnosis at the Infectious Diseases Clinic of the University ‘G. D’Annunzio’, Chieti, Italy from January 2013 to December 2019. For… Show more

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Cited by 4 publications
(6 citation statements)
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“…Table 1 presents the results obtained from strategy 1 (imaging examinations) over the entire literature search period and includes 27 articles [ 7 , 11 , 20 , 21 , 25 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ]. Table 2 presents the results obtained from strategy 2 (pathology and histopathology), also for the whole period [ 52 , 53 ].…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Table 1 presents the results obtained from strategy 1 (imaging examinations) over the entire literature search period and includes 27 articles [ 7 , 11 , 20 , 21 , 25 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ]. Table 2 presents the results obtained from strategy 2 (pathology and histopathology), also for the whole period [ 52 , 53 ].…”
Section: Resultsmentioning
confidence: 99%
“…The imaging tests predominantly used to detect embolisms were USG [ 11 ], CT [ 7 , 11 , 21 , 25 , 30 , 31 , 32 , 33 , 34 , 41 , 43 , 45 , 46 , 50 ], MRI [ 43 , 51 ], 18 F-FDG PET/CT [ 20 , 29 , 35 , 38 , 39 , 40 , 42 , 44 , 47 , 48 , 49 , 50 , 51 ], SPECT/CT [ 29 , 36 ], and CEUS [ 37 ]. More recent studies tended to use PET-CT, although many still used conventional CT as it is more readily available.…”
Section: Resultsmentioning
confidence: 99%
“…Finally, the indications for transcatheter procedures extend to include the elderly and frail and these patients are at greater risk of complications with increased mortality rates than prior cohorts. Increasing age, which is a trend also observed in patients admitted to the ICU for IE, seems associated with mortality as well [16,17,19,21]. Additional factors which have been associated with complications of IE, are congenital heart disease, congestive heart failure, a heavy burden of comorbidities and specific causative pathogens, that is S. aureus and fungi [3 & ].…”
Section: Epidemiology and Pathophysiologymentioning
confidence: 99%
“…Increased D-dimer levels were also associated with in-hospital mortality and 6-month mortality in an observational study of 613 non-ICU patients [23]. In a single center retrospective study in non-ICU patients, elevated serum procalcitonin concentrations both at admission and at 48–72 h were associated with in-hospital mortality [16]. Conversely, cardiac surgery is often reported as a protective factor regarding mortality [4 ▪ ,18,19].…”
Section: Introductionmentioning
confidence: 99%
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