2019
DOI: 10.1093/jbcr/irz041
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Risk Factors Associated with the Development of Transaminitis in Oxandrolone-Treated Adult Burn Patients

Abstract: Oxandrolone has proven benefits in thermal burn injury and has become a standard of care. Transaminitis is the most frequent side effect of oxandrolone use, although no risk factors have been identified that increase the risk of transaminitis. The objective was to evaluate the frequency of transaminitis while on oxandrolone and to identify risk factors leading to an increased risk of transaminitis in adult burn patients. This multicenter retrospective risk factor analysis compared two patient groups with and w… Show more

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Cited by 4 publications
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“…Specifically, patients who are younger and have concurrent amiodarone or vasopressor use have the highest risk of developing oxandrolone-induced transaminitis. 6 These adverse effects have been shown to develop following large doses and/or chronic use of oxandrolone. However, the elevation of transaminases returns to normal once oxandrolone is discontinued.…”
Section: Oxandrolone Pharmacology and Guidelinesmentioning
confidence: 99%
“…Specifically, patients who are younger and have concurrent amiodarone or vasopressor use have the highest risk of developing oxandrolone-induced transaminitis. 6 These adverse effects have been shown to develop following large doses and/or chronic use of oxandrolone. However, the elevation of transaminases returns to normal once oxandrolone is discontinued.…”
Section: Oxandrolone Pharmacology and Guidelinesmentioning
confidence: 99%