Risk Factors, Clinical Characteristics, Management, and Outcomes of Musculoskeletal Fungal Infection at Thailand’s Largest National Tertiary Referral Center

Chokevittaya, Piyaporn; Chayakulkeeree, Methee; Katchamart, Wanruchada

doi:10.3390/jof8020191

Cited by 3 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chokevittaya et al . [ 24 ] in 2022 published a series of four cases of C. neoformans tibial osteomyelitis in Thailand, raising the total number of tibia involvement to nine (Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cryptococcus neoformans osteomyelitis of the tibia: a case report and review of the literature

et al. 2023

View full text Add to dashboard Cite

Introduction Osteomyelitis is a bone inflammation that can be related to various infectious agents. As with any other type of inflammation, the prevailing symptoms and signs may include redness, swelling, pain, and heat. Fungal osteomyelitis is rare and usually found in immune-compromised patients. Case presentation A non-human immunodeficiency virus immunocompromised Greek female patient, 82 years old, visited the emergency department due to a 3 day pain located mainly over the left tibia’s anterior surface, accompanied by swelling and redness. There was also a subcutaneous lesion of her left breast. Medical history revealed that the patient had an unmasked close contact with pigeons, a main host of the disease. Initial x-ray imaging showed an osteolytic area in the upper third of the tibial diaphysis. The patient was admitted and underwent a computed tomography-guided biopsy. The specimen revealed a Cryptococcus neoformans infection of the bone and the breast. She was treated with 400 mg fluconazole twice a day for 3 weeks while in hospital and 200 mg twice a day upon discharge for 9 months. After that, she underwent surgical debridement because of lasting local irritation. She was closely monitored in our outpatient office, and in her last visit, 1 year after the initial admission, inflammatory signs had regressed vastly. Conclusions To our knowledge, this is the ninth cryptococcal osteomyelitis of the tibia to be recorded since 1974, and the most unusual finding was the bifocal nature of the infection, affecting both the tibia and the breast.

show abstract

“…Chokevittaya et al . [ 24 ] in 2022 published a series of four cases of C. neoformans tibial osteomyelitis in Thailand, raising the total number of tibia involvement to nine (Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

“…[ 68 ] Pregnancy Tibia Surgical debridement + antifungal treatment Chokevittaya et al . (4) [ 24 ] NR Tibia NR Present case Rheumatoid arthritis Tibia, breast Surgical debridement + antifungal treatment Number in brackets: number of more than one cases presented by the same author NR not reported …”

Section: Discussionmentioning

confidence: 99%