Risk factors, diagnosis and management of venous thromboembolic disease in pregnancy

Abstract

Venous thromboembolism (VTE) in pregnancy is a leading cause of maternal morbidity and mortality. However, despite the significant associated clinical burden and potentially devastating societal impact, there is still a paucity of data surrounding its prevention and management. Consequently, international guideline recommendations vary widely. Exclusion of pregnant women from clinical trials in the past has contributed to knowledge gaps. However, recently published and ongoing studies demonstrate that excellent clinical trials in pregnancy are achievable. This review will discuss prevention, diagnosis and treatment of VTE in pregnancy, and will also explore priorities for future research.Educational aimsTo gain an understanding of current knowledge on risk factors for pregnancy-associated venous thromboembolism (PA-VTE).To gain an understanding of the diagnosis of PA-VTE.To review up-to-date approaches to preventing and treating PA-VTE.To discuss possible limitations in current research and areas which require improvement.

Effect of Nursing Intervention on Nurses' Performance regarding the Prevention of Deep Vein Thrombosis among Postpartum Women

“…Venous thromboembolism (VTE) is a major health concern during the postpartum period. While the risk of VTE is fivefold during pregnancy, this risk is increased to 60-fold during the postpartum period (1)(2)(3). It is considered one of the leading causes of maternal morbidity and mortality, accounting for 10-30% of all maternal deaths in the United States and other Western countries (2,4).…”

What we do and do not know about managing respiratory disease in pregnancy

“…Happily, it is highly unusual for most respiratory disorders to cause death during pregnancy, but thromboembolic disease, including pulmonary embolism, remains one of the most important causes of maternal mortality [7]. EDEBIRI and NÍ ÁINLE [8] review the diagnosis and management of venous thromboembolic disease in pregnancy, including a discussion of the utility in pregnant women of the available clinical screening tools for venous thromboembolism.…”