Risk Factors for a Second Episode of Hemoptysis

Seki, Nobuhiko; Shiozaki, Go; Ota, Mayuko; Ota, Shuji; Seki, Reishi; Seto, Takashi; Uematsu, Kazutsugu; Eguchi, Katsumi

doi:10.4137/ccrpm.s1064

Cited by 4 publications

(4 citation statements)

References 25 publications

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“…Most of the cases of recurrent cases are positive for bacteria from bronchial lavage and ethiology is known. Regardless of the volume of the initial episode, the failure to determine the etiology of an initial episode of hemoptysis was associated with an increased risk of a massive second episode (P = 0.040), whereas in a study done by Nobuhiko Seki et al; odds ratio of 13.5, P = 0.001 in the isolation of bacteria from bronchial lavage fluid was determined and odds ratio of 7.0, P = 0.014 in the failure to determine the cause of the initial episode of hemoptysis were significant independent predictors of a second episode of hemoptysis [6]. Even if colonization, representing host-bacterial equilibrium, had occurred, isolation of either Pseudomonas aeruginosa or Haemophilus influenzae increased the likelihood of a second episode of hemoptysis (P = 0.077) by subset analysis .…”

Section: Discussionmentioning

confidence: 86%

Risk Factors for a Second Episode of Hemoptysis

Varma¹,

Reddy²

2018

APJHS

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Background: Of lung diseases, Hemoptysis is an alarming symptom. It is difficult for clinicians to choose how to deal with patients who had a single episode of hemoptysis, especially if the cause is unknown. Using multivariate analysis, investigations were done to see whether any factor in the initial episode could be a predictor of second episode. Aim: In this study, by using multivariate analysis, to check whether any clinical factor present during initial episode of hemoptysis are useful predictors of second episode of hemoptysis. Materials and Methods: 100 Patients with initial episode of hemoptysis, their medical records were reviewed. Patients who had undergone both chest CT and bronchoscopic examinations were selected in the study. Results: 100 patients were selected. From bronchial lavage fluid, active and inactive fluid were isolated in 17 (17%) cases. On further examination, diagnosis was not established in 27 (27%) cases. The predictors of hemoptysis were bacteria from bronchial lavage which has shown a 62 patients were negative for bacteria and 7 patients were positive for bacteria out of a total of 69 patients in initial episode and 21 patients showed negative to bacteria and 10 patients showed positive to bacteria out of a total of 31 patients in reccurent episode. All the demographic details of initial episode and recurrent cases are insignificant on comparision. Most of the cases of recurrent cases are positive for bacteria from bronchial lavage and ethiology is known. Regardless of the volume of the initial episode, the failure to determine the etiology of an initial episode of hemoptysis was associated with an increased risk of a massive second episode (P = 0.040).Conclusion: There is an increased possibility of a second episode of hemoptysis in patients with bacterial colonization of the respiratory tract or an initial episode of hemoptysis of unknown etiology.

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Section: Discussionmentioning

confidence: 86%

Risk Factors for a Second Episode of Hemoptysis

Varma¹,

Reddy²

2018

APJHS

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“…Bizim bulgularımız literatürdeki bulgulara benzemekte olup FOB' un özellikle akciğer kanserlerinin ve hemoptizinin teşhisinde ve tedavisinde kullanılan yöntemlerden biri olduğunu bir kez daha göstermektedir. (14,17).…”

Section: Discussionunclassified

Kli̇ni̇ği̇mi̇ze Hemopti̇zi̇ Şi̇kâyeti̇yle Başvuran Hastalarda Hemopti̇zi̇ Etyoloji̇leri̇ Ve Tedavi̇ Yaklaşimlari

Balcı

Çilekar

2021

Kocatepe Tıp Dergisi

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Hemoptizi pulmoner veya bronşiyal vasküler sistemden kaynaklanan kanamaların sonucu olarak akciğer veya bronşlardan gelen kanın tükürülmesidir. Birçok hastalık için önemli bir ipucu olabilmektedir. Bazı durumlarda da zamanında ve etkili müdahale olmaz ise ölümcül sonuçlar doğurabilir. Çalışmamızda kliniğimizde 3 yıllık süre içinde hemoptizi şikayeti ile takip edilen vakalara yaklaşımımız ve bu vakaların etiyolojilerini literatür eşliğinde değerlendirmeyi amaçladık. GEREÇ VE YÖNTEM:Çalışmamız retrospektif dosya taraması şeklinde planlandı. Hastanemizde, göğüs hastalıkları kliniğinde son 3 yıllık süre (Ocak 2017-Ocak 2020) içinde çeşitli nedenlerle yatırılarak takip edilen toplam 3150 hastadan, hemoptizi tarifleyen ve yeterli dosya bilgisine ulaşılan 200 (%6,34) hasta çalışmaya dahil edildi. BULGULAR:Hastaların hemoptizi etyolojileri değerlendirildiğinde en sık etiyolojik faktörün 63 (%31,5) akciğer kanseri olduğu görüldü. PA akciğer grafisi 32 (%16) hastada normal, 168 (%84) hastada diğer akciğer hastalıkları (Bronşiektazi, organize pnömoni, tüberküloz v.b.) saptandı. Bilgisayarlı tomografi (BT)'de saptanan en sık patolojik bulgu 90 (%45) hastada konsolidasyon (infiltrasyon) idi. SONUÇ:Hemoptizi şikâyeti ile başvuran hastalarda doğru klinik süreçler (anamnez, klinik ve radyolojik bulgular ile gerekirse invaziv ileri tanı teknikleri) kullanıldığında tanıya ulaşma olasılığı bizim çalışmamızda olduğu gibi %90'ın üzerine çıkmaktadır. Bu yüzden Klinik ve radyolojik bulgulara fiberoptik bronkoskopi (FOB) kullanımının eklenmesi, hemoptizi tanı ve tedavisinde daha faydalı olacaktır.

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“…However, significant statistical heterogeneities were observed only at the analysis of the hemoptysis cessation rate. Fourth, some factors, such as smoking, malignancy, pulmonary infection, and anti-coagulant drug use, [41][42][43] were associated with increased rate of mortality and hemoptysis recurrence. These confounding factors were not fully disclosed in some studies (Supplementary Table 3, http:// links.lww.com/MD/G77).…”

Section: Discussionmentioning

confidence: 99%

Does tranexamic acid reduce risk of mortality on patients with hemoptysis?

et al. 2021

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Background: Although tranexamic acid (TXA), a readily accessible antifibrinolytic agent, is widely adopted in hemorrhage scenarios, its role on mortality in patients with hemoptysis remains uncertain. New evidence is yet to be generated to evaluate the risk of mortality after using TXA in patients with hemoptysis. Methods: PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus databases were searched from inception to May 2020. Randomized controlled trials and observational studies that evaluated the effect of TXA on patients with hemoptysis were included. Data were independently extracted by 2 reviewers and synthesized using a random-effects model. Main results: Five studies with a total of 20,047 patients were analyzed. When compared with the control, administration of TXA was associated with a reduction in short-term mortality (risk ratio = 0.78, 95% confidence interval [CI] 0.72–0.85; I 2 = 0), shorter bleeding time (mean difference = − 24.61 hours, 95% CI − 35.96 to −13.26, I 2 = 0), shorter length of hospital stay (mean difference = −1.94 days, 95% CI −2.48 to −1.40, I 2 = 0), and lower need for intervention (risk ratio = 0.38, 95% CI 0.16–0.87, I 2 = 0) in patients with hemoptysis. Compared with control, administration of TXA did not cause increased major or minor adverse effects. Conclusions: TXA provided benefits in terms of a lower short-term mortality rate, less bleeding time, shorter length of hospital stays, and less need for intervention in patients with hemoptysis. Use of TXA was not associated with increased adverse effects.

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Risk Factors for a Second Episode of Hemoptysis

Cited by 4 publications

References 25 publications

Risk Factors for a Second Episode of Hemoptysis

Risk Factors for a Second Episode of Hemoptysis

Kli̇ni̇ği̇mi̇ze Hemopti̇zi̇ Şi̇kâyeti̇yle Başvuran Hastalarda Hemopti̇zi̇ Etyoloji̇leri̇ Ve Tedavi̇ Yaklaşimlari

Does tranexamic acid reduce risk of mortality on patients with hemoptysis?

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