2017
DOI: 10.1183/13993003.00489-2017
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Risk factors for admission to hospital with laboratory-confirmed influenza in young children: birth cohort study

Abstract: We determined risk factors for influenza hospital admission in children aged <2 years to guide the design of paediatric vaccination programmes.We linked all singleton live births in Scotland from 2007 to 2015 to hospital administrative data and influenza laboratory reports. Cox proportional hazard models were used to identify birth and family risk factors for influenza admissions.There were 1115 influenza admissions among 424 048 children. 85.1% of admitted children were born at term and were not in a high-ris… Show more

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Cited by 26 publications
(26 citation statements)
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“…The cohort study of 402 762 singleton livebirths in Scotland from 2007 to 2015 used data linkages between birth and death registration, hospital administrative data and influenza laboratory reports from 2009 to 2015 (six influenza seasons). They identified 1019 influenza-confirmed hospital admissions during the study period, or 2.57 per 1000 child-years in children aged less than 6 months and 2.07 per 1000 child years in children aged 6-23 months [10]. The study findings highlight several limitations of current influenza immunisation programmes.…”
mentioning
confidence: 87%
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“…The cohort study of 402 762 singleton livebirths in Scotland from 2007 to 2015 used data linkages between birth and death registration, hospital administrative data and influenza laboratory reports from 2009 to 2015 (six influenza seasons). They identified 1019 influenza-confirmed hospital admissions during the study period, or 2.57 per 1000 child-years in children aged less than 6 months and 2.07 per 1000 child years in children aged 6-23 months [10]. The study findings highlight several limitations of current influenza immunisation programmes.…”
mentioning
confidence: 87%
“…Targeting "at-risk" groups is likely to have limited impact on hospitalisations HARDELID et al [10] found that 85% of influenza-related hospital admissions in children aged 6-23 months occurred in those who were not known to be in a clinical risk group. In addition, targeting preventative strategies at these risk groups would only prevent 3-6% of hospital admissions.…”
Section: Problems With Current Vaccination Strategiesmentioning
confidence: 99%
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“…Fifth, unmeasured environmental and social influences could confound the relationship between maternal recall of childhood TLE and the risk of infant bronchiolitis seen by health care services. Both contact with older siblings and deprivation are strongly associated with earlier age of bronchiolitis and with hospitalisation . The study by Adgent et al did not account for parity, other children in the household or involvement of other care givers with children, relative deprivation, or environmental risk factors for childhood respiratory disease.…”
Section: Do These Findings Provide Evidence Of Enduring Maternal Strementioning
confidence: 99%