“…In addition, the opposite may happen as well: there is an increased risk for relatives of patients with AN and BN to develop subclinical forms of ED, major depressive disorder, obsessive-compulsive disorder, and anxiety disorders (Lilenfeld et al, 1998). What is curious to note is that, on the one hand, having a sibling with AN predisposes to the development of AN (Felker & Stivers, 1994;Machado et al, adolescence, and the level of affective expression of the family seems to be relate to ED risk during adolescence (Felker & Stivers, 1994), but our review has highlighted that all those features of what could be described as a "toxic" (Mangweth et al, 2005) • dysfunctional interaction during feeding (in IA) (Ammaniti et al, 2010) • attachment insecurity (Chatoor et al, 2000) • dependence (Chatoor et al, 2000;Lyon et al, 1997) • maternal diet (Haynos et al, 2016) Table 3 Main intrafamilial risk factors for AN Intrafamilial risk factors for AN • Increased food intake in the family (Hilbert et al, 2014) • Perfectionism (Hilbert et al, 2014;Pike et al, 2008Pike et al, , 2021 • Higher parental demands (Pike et al, 2008) • Emotional reactivity (Lyke & Matsen, 2013) • Family taboos regarding nudity and sexuality (Mangweth et al, 2005) • Low familial involvement (Haynos et al, 2016) • Negative affectivity (Pike et al, 2008(Pike et al, , 2021 • Family discord (Pike et al, 2008) • Negative family history for ED (as a predictor of poor outcome) (Ackard et al, 2014) • Family history of depression (Lyon et al, 1997) • Positive family history for psychiatric disorders Pike et al, 2021) • Affective disorders in family members (Steinhausen et al, 2015) • Alcohol and drug abuse (Lyon et al, 1997) • Having a sibling with AN (Machado et al, 2014;Steinhausen et al, 2015) • Relational trauma…”